Oh Andrea S, Lynch David A
Department of Radiology, University of California Los Angeles, 757 Westwood Plaza, Box 957437, Los Angeles, CA 90095-7437, USA.
Department of Radiology, National Jewish Health, 1400 Jackson Street, Room K012f, Denver, CO 80206, USA.
Radiol Clin North Am. 2022 Nov;60(6):889-899. doi: 10.1016/j.rcl.2022.06.002. Epub 2022 Sep 3.
Interstitial lung abnormalities (ILAs) are specific computed tomography (CT) findings that are potentially compatible with interstitial lung disease (ILD) in patients without clinical suspicion for disease. ILAs are associated with adverse clinical outcomes including increased mortality, imaging progression and lung function decline, and increased lung injury risk with lung cancer therapies. It is expected that identification of ILAs will increase with implementation of lung cancer screening and diagnostic CT imaging for workup of other pathologies. As such, radiologists will play a critical role in the diagnosis and management of ILAs.
间质性肺异常(ILA)是特定的计算机断层扫描(CT)表现,在无疾病临床怀疑的患者中可能与间质性肺疾病(ILD)相符。ILA与不良临床结局相关,包括死亡率增加、影像进展和肺功能下降,以及肺癌治疗导致的肺损伤风险增加。预计随着肺癌筛查以及针对其他病理情况的诊断性CT成像的实施,ILA的检出率将会增加。因此,放射科医生在ILA的诊断和管理中将发挥关键作用。