Bennett Audrey L, Schwartz David A
Vanderbilt University Medical Center, 1301 Medical Center Drive, 1600 The Vanderbilt Clinic, Nashville, TN 37232, USA.
Vanderbilt University Medical Center, Inflammatory Bowel Disease Clinic, 719 Thompson Lane, Suite 20500, Nashville, TN 37204, USA.
Gastrointest Endosc Clin N Am. 2022 Oct;32(4):747-759. doi: 10.1016/j.giec.2022.04.005. Epub 2022 Sep 7.
Perianal Crohn's disease is associated with decreased quality of life, high morbidity, and high health care use. Treatment goals are to provide infection control, stop fistula drainage, and heal fistula tracts while preserving the anorectal sphincter. Treatment includes a combination of medical and surgical intervention, but new techniques are using interventional endoscopy to act as either a bridge to surgery or to decrease the need for surgical intervention. The decision on which approach to pursue requires knowledge of prior surgery, altered anatomy, prior fistula treatment, and imaging and endoscopic evaluation of fistula complexity, mucosal involvement, and associated stricture or abscess.
肛周克罗恩病与生活质量下降、高发病率及高医疗资源利用率相关。治疗目标是控制感染、停止瘘管引流并治愈瘘管通道,同时保留肛门直肠括约肌。治疗包括药物和手术干预相结合,但新技术正在使用介入性内镜检查,以作为手术的桥梁或减少手术干预的需求。决定采用哪种方法需要了解既往手术情况、解剖结构改变、既往瘘管治疗情况以及对瘘管复杂性、黏膜受累情况以及相关狭窄或脓肿的影像学和内镜评估。