Sohrabi Masoudreza, Bahrami Somayeh, Mosalli Mozhdeh, Khaleghian Mohsen, Obaidinia Mobin
Gastrointestinal and liver Diseases Research Center, Iran University of Medical Sciences, Tehran, Iran.
Department of General Surgery, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Middle East J Dig Dis. 2024 Apr;16(2):76-85. doi: 10.34172/mejdd.2024.373. Epub 2024 Apr 30.
Anal fistula has been a challenging clinical issue for years due to its complex pathogenesis. The risk of frequent recurrence and incontinence complicates long-term treatment. Recent scientific literature has reviewed new techniques used for anal fistula treatment in recent years, assessing the advantages and disadvantages of each based on clinical outcomes. Although surgery is the main method used to treat anal fistula, there is no simple technique that can completely heal complex anal fistula. The surgical treatment should consider the healing outcome and the protection of anal function comprehensively. Several innovative techniques have emerged in recent years, such as combined techniques based on drainage seton and LIFT-plug, which appear to be relatively effective therapies. However, more multi-center prospective trials with long-term follow-up are needed to validate their effectiveness. In some situations, medical treatment may also be considered.
由于肛瘘发病机制复杂，多年来一直是一个具有挑战性的临床问题。频繁复发和失禁的风险使长期治疗变得复杂。最近的科学文献回顾了近年来用于肛瘘治疗的新技术，并根据临床结果评估了每种技术的优缺点。虽然手术是治疗肛瘘的主要方法，但没有一种简单的技术能够完全治愈复杂性肛瘘。手术治疗应综合考虑愈合效果和肛门功能的保护。近年来出现了一些创新技术，如基于引流挂线和LIFT封堵术的联合技术，这些技术似乎是相对有效的治疗方法。然而，需要更多的多中心前瞻性长期随访试验来验证其有效性。在某些情况下，也可以考虑药物治疗。
