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剖宫产术中相关围产儿死亡率在医院间的差异是否反映了护理质量的差异?布基纳法索 21 家医院的横断面研究。

Does hospital variation in intrapartum-related perinatal mortality among caesarean births reflect differences in quality of care? Cross-sectional study in 21 hospitals in Burkina Faso.

机构信息

Population, Policy and Practice, University College London Institute of Child Health, London, UK

The Health Foundation, London, UK.

出版信息

BMJ Open. 2022 Oct 6;12(10):e055241. doi: 10.1136/bmjopen-2021-055241.

Abstract

OBJECTIVES

To examine hospital variation in crude and risk-adjusted rates of intrapartum-related perinatal mortality among caesarean births.

DESIGN

Secondary analysis of data from the DECIDE (DECIsion for caesarean DElivery) cluster randomised trial postintervention phase.

SETTING

21 district and regional hospitals in Burkina Faso.

PARTICIPANTS

All 5134 women giving birth by caesarean section in a 6-month period in 2016.

PRIMARY OUTCOME MEASURE

Intrapartum-related perinatal mortality (fresh stillbirth or neonatal death within 24 hours of birth).

RESULTS

Almost 1 in 10 of 5134 women giving birth by caesarean experienced an intrapartum-related perinatal death. Crude mortality rates varied substantially from 21 to 189 per 1000 between hospitals. Variation was markedly reduced after adjusting for case mix differences (the median OR decreased from 1.9 (95% CI 1.5 to 2.5) to 1.3 (95% CI 1.2 to 1.7)). However, higher and more variable adjusted mortality persisted among hospitals performing fewer caesareans per month. Additionally, adjusting for caesarean care components did not further reduce variation (median OR=1.4 (95% CI 1.2 to 1.8)).

CONCLUSIONS

There is a high burden of intrapartum-related perinatal deaths among caesarean births in Burkina Faso and sub-Saharan Africa more widely. Variation in adjusted mortality rates indicates likely differences in quality of caesarean care between hospitals, particularly lower volume hospitals. Improving access to and quality of emergency obstetric and newborn care is an important priority for improving survival of babies at birth.

TRIAL REGISTRATION NUMBER

ISRCTN48510263.

摘要

目的

研究剖宫产术中与围产儿相关的死亡率的粗率和风险调整率在医院间的差异。

设计

DECIDE(剖宫产决策)集群随机试验干预后阶段的数据的二次分析。

地点

布基纳法索的 21 个区和地区医院。

参与者

2016 年 6 个月内所有 5134 名剖宫产分娩的妇女。

主要结局测量

与产时相关的围产儿死亡(新鲜死产或出生后 24 小时内新生儿死亡)。

结果

5134 名剖宫产分娩的妇女中,近 10 人中有 1 人经历了与产时相关的围产儿死亡。医院间的死亡率差异很大,从每 1000 例中的 21 例到 189 例不等。调整病例组合差异后,差异明显减少(中位数 OR 从 1.9(95%CI 1.5 至 2.5)降至 1.3(95%CI 1.2 至 1.7))。然而,每月行剖宫产术较少的医院的死亡率更高且更具差异。此外,调整剖宫产护理成分并不能进一步减少差异(中位数 OR=1.4(95%CI 1.2 至 1.8))。

结论

布基纳法索和更广泛的撒哈拉以南非洲地区剖宫产术中与围产儿相关的死亡负担很高。调整后的死亡率差异表明医院间剖宫产护理质量可能存在差异,特别是低容量医院。改善紧急产科和新生儿护理的可及性和质量是提高出生时婴儿存活率的重要优先事项。

试验注册

ISRCTN48510263。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e22/9540846/b6e7d2597388/bmjopen-2021-055241f01.jpg

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