Department of Obstetrics and Gynecology, "Tor Vergata" University, Rome, Italy.
Department of Obstetrics and Gynecology, "Sandro Pertini" Hospital, Rome, Italy.
Gynecol Endocrinol. 2022 Nov;38(11):988-991. doi: 10.1080/09513590.2022.2132224. Epub 2022 Oct 6.
The aim of the study was to evaluate the impact of SARS-CoV-2 vaccination on quality of life, psychological aspect and sexual life in a group of Italian postmenopausal women during the COVID-19 pandemic.
The study was a prospective, observational analysis of postmenopausal women before and after the COVID-19 vaccination. The population previously answered different questionnaires, such as the Female Sexual Function Index (FSFI), the Female Sexual Distress Scale (FSDS), the 36-Item Short Form Survey (SF-36) and the Hospital Anxiety and Depression Scale (HADS). Twelve weeks after the end of the vaccine cycle, these women were invited to complete the same questionnaires by e-mail to evaluate if vaccination coverage could positively impact the quality of life of postmenopausal women. The Patient Impression of Global Improvement (PGI-I) after three months of treatment was also calculated.
A total of 114 patients were reported. The median age was 60.96 (52-66) years. Mean sexual intercourses/month increased from 1.28 ± 1.23 to 4.21 ± 1.80 ( = 0.001). The FSFI increased (19.22 ± 3.31 vs 29.24 ± 4.21, < 0.0001) and the FSDS decreased significantly (20.12 ± 5.23 vs 9.32 ± 5.55, < 0.0001) 12 weeks after vaccination coverage. The SF-36 increased from 64.23 ± 11.76 to 82.21 ± 10.24 ( < .0001) and the HADS questionnaire improved significantly from 9.3 ± 2.73 to 5.1 ± 1.34 after the COVID-19 vaccine execution (<.0001).
The spread of COVID-19 vaccine coverage positively influenced sexual function, quality of life and psychological aspect in postmenopausal women.
本研究旨在评估 SARS-CoV-2 疫苗接种对意大利一组绝经后女性在 COVID-19 大流行期间生活质量、心理方面和性生活的影响。
这是一项针对绝经后女性的前瞻性、观察性分析，在 COVID-19 疫苗接种前后进行。该人群之前回答了不同的问卷，例如女性性功能指数（FSFI）、女性性功能障碍量表（FSDS）、36 项简明健康调查问卷（SF-36）和医院焦虑抑郁量表（HADS）。疫苗接种周期结束后 12 周，通过电子邮件邀请这些女性填写相同的问卷，以评估疫苗接种覆盖率是否能对绝经后女性的生活质量产生积极影响。还计算了治疗三个月后的患者总体改善印象（PGI-I）。
共报告了 114 例患者。中位年龄为 60.96（52-66）岁。每月平均性生活次数从 1.28±1.23 增加到 4.21±1.80（ = 0.001）。FSFI 增加（19.22±3.31 与 29.24±4.21， < 0.0001），FSDS 显著降低（20.12±5.23 与 9.32±5.55， < 0.0001）接种疫苗覆盖率后 12 周。SF-36 从 64.23±11.76 增加到 82.21±10.24（ <.0001），HADS 问卷从 COVID-19 疫苗接种后从 9.3±2.73 显著改善到 5.1±1.34（ <.0001）。
COVID-19 疫苗接种的普及对绝经后女性的性功能、生活质量和心理方面产生了积极影响。
