[Serum calcium, inorganic phosphorus and alkaline phosphatase levels in sheep with deformities of the extremities].

Deformations of skeleton have appeared in 40.0% of rams and in 10.0% of ewes 9 months old fed concentrates and libitum. The ration of Ca:P in a daily fed ration was 0.832:1.0. The contend of Ca in sera of sick animals was normal, however, the level of inorganic P was elevated by 12.32 mg/100 ml in young rams and by 11.20 g/100 ml in young ewes. The activity of alkaline phosphatase exceeded almost three times the normal value of this enzyme and it reached 44.6 K-A in young rams and 32.8 i K-A in young ewes. In control 9 months old sheep under controlled feeding the content of the examined minerals and activity of alkaline phosphatase were in normal limits. It was found a statistically significant difference in the content of inorganic P and the activity of alkaline phosphatase in experimental and control animals. It was corrected feeding of the experimental sheep in which successive examinations performed at the age of 12 and 18 months did not reveal statistically significant differences in comparison to control animals. The increase of the activity of alkaline phosphatase in 9 months old experimental sheep is the result of disturbances in Calcium-Phosphorus balance due to unproper mineral feeding.