Department of Microbiology, Prasad Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
Ann Afr Med. 2022 Jul-Sep;21(3):193-197. doi: 10.4103/aam.aam_110_20.
The emergence of Enterococcus as an important nosocomial pathogen is mainly attributed to its inherent resistance to commonly used antibiotics and now in recent times, it has acquired resistance to other available therapeutic options as well.
Enterococcus isolates from clinical samples received in the department of microbiology over a period of 1 year were included in the study. Isolates were identified and species determined by standard methods. Antibiotic susceptibility test was done by Kirby Bauer disc diffusion test. Epsilometer test was done to determine the minimum inhibitory concentration for vancomycin.
A total of 145 Enterococcus isolates were obtained; 73 (50.3%) isolates were identified as Enterococcus faecalis, 69 (47.5%) Enterococcus faecium, 2 (1.3%) Enterococcus durans and 1 (0.68%) as Enterococcus gallinarum. Most of the isolates were from urine samples (125, 86.2%); followed by pus (16, 11.03%). Vancomycin resistance was seen in 14 (9.6%) isolates while linezolid resistance was seen in 8 (5.5%) isolates.
E. faecalis is the most common clinical species isolated from clinical samples and the emergence of linezolid-resistant enterococci from the hospital is a matter of concern as till now it is considered to be the last resort for treatment in patients infected with vancomycin-resistant enterococci.
肠球菌作为一种重要的医院获得性病原体的出现，主要归因于其对常用抗生素的固有耐药性，而现在，它已经获得了对其他现有治疗选择的耐药性。
在微生物学系收到的临床标本中，对肠球菌分离株进行了为期 1 年的研究。采用标准方法对分离株进行鉴定和种属鉴定。采用 Kirby Bauer 纸片扩散法进行抗生素敏感性试验。采用 Epsilometer 试验测定万古霉素的最低抑菌浓度。
共获得 145 株肠球菌分离株；73 株（50.3%）鉴定为粪肠球菌，69 株（47.5%）鉴定为屎肠球菌，2 株（1.3%）鉴定为坚韧肠球菌，1 株（0.68%）鉴定为鸡肠球菌。大多数分离株来自尿液标本（125 株，86.2%）；其次是脓液（16 株，11.03%）。14 株（9.6%）分离株对万古霉素耐药，8 株（5.5%）分离株对利奈唑胺耐药。
粪肠球菌是从临床标本中分离出来的最常见的临床菌株，而医院中出现耐利奈唑胺的肠球菌是一个值得关注的问题，因为到目前为止，它被认为是治疗耐万古霉素肠球菌感染患者的最后手段。
