Wang Zizhen, Ma Haowen, Zhang Yu, Yuan Yifei, Liu Yan, Chen Yueguo
Department of Ophthalmology, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing, 100191, People's Republic of China.
Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing, 100191, People's Republic of China.
Ophthalmol Ther. 2022 Dec;11(6):2243-2257. doi: 10.1007/s40123-022-00579-8. Epub 2022 Oct 7.
This study evaluated the changes and explored influential factors in the anterior chamber after femtosecond laser-assisted in situ keratomileusis (FS-LASIK) on the basis of patients with different degrees of myopia, refractive status, and age.
Patients underwent uneventful FS-LASIK for the treatment of ametropia. All patients with myopia were classified into a low age group (18-40 years) or high age group (> 40 years). Patients in the low age group (18-40 years) were subdivided into myopia and hyperopia groups. According to the preoperative spherical equivalent values, the myopia group was further divided into low myopia, moderate myopia, and high myopia groups. We measured the magnitude of anterior chamber depth (ACD), angle (ACA), volume (ACV), lens rise, central corneal thickness (CCT), and mean pupil power (MPP) of all patients using Sirius (version 3.2, CSO, Italy) before and 3 months post operation.
A total of 140 eyes of 87 patients were evaluated. The magnitudes of ACD, ACA, and ACV decreased significantly postoperatively in both low age (P < 0.001, P < 0.001, P < 0.001, respectively) and high age group (P < 0.001, P < 0.001, P < 0.001, respectively) of patients with myopia, while an increasing tendency of ACD (2.85 ± 0.38 mm preoperatively vs 2.89 ± 0.09 mm postoperatively) and ACA (39.16° ± 7.30° preoperatively vs 39.37° ± 7.68° postoperatively) was found in hyperopia. There was no correlation between different degrees of myopia and the changes in the anterior chamber.
Anterior chamber parameters decreased significantly and approximately in the same degree in low and high age groups postoperatively, while an increasing tendency of ACD and ACA was found in hyperopia, indicating that it is probably a corneal magnification effect that influences changes in the anterior chamber.
本研究基于不同近视程度、屈光状态和年龄的患者，评估了飞秒激光原位角膜磨镶术（FS-LASIK）后前房的变化并探究了影响因素。
患者接受了平稳的FS-LASIK手术以治疗屈光不正。所有近视患者被分为低年龄组（18 - 40岁）或高年龄组（> 40岁）。低年龄组（18 - 40岁）的患者又被细分为近视组和远视组。根据术前等效球镜值，近视组进一步分为低度近视、中度近视和高度近视组。我们使用Sirius（版本3.2，CSO，意大利）在所有患者术前及术后3个月测量前房深度（ACD）、房角（ACA）、房容积（ACV）、晶状体抬高、中央角膜厚度（CCT）和平均瞳孔屈光度（MPP）。
共评估了87例患者的140只眼。近视患者的低年龄组（P < 0.001，P < 0.001，P < 0.001）和高年龄组（P < 0.001，P < 0.001，P < 0.001）术后ACD、ACA和ACV的数值均显著降低，而远视患者中ACD（术前2.85 ± 0.38 mm，术后2.89 ± 0.09 mm）和ACA（术前39.16° ± 7.30°，术后39.37° ± 7.68°）有增加趋势。不同程度近视与前房变化之间无相关性。
术后低年龄组和高年龄组前房参数均显著降低且降低程度大致相同，而远视患者中ACD和ACA有增加趋势，表明影响前房变化的可能是角膜放大效应。
