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[保护性呼吸反射强度的电生理评估]

[Electrophysiological evaluation of the intensity of protective respiratory reflexes].

作者信息

Kulik A M, Ciacová A, Korpas J, Tarakanov I A, Gul'ian V M

出版信息

Biull Eksp Biol Med. 1987 Jul;104(7):5-8.

PMID:3620650
Abstract

The impulse activity of bulbar respiratory neurons and the electrical activity of main respiratory muscles were studied stereotaxically and electromyographically on 21 male and female cats anesthetized with pentobarbital (40 mg/kg, i.p.) during defensive respiratory (expiratory and coughing) reflexes. During stimulation of laryngopharyngeal and tracheobronchial receptors, a pronounced focus of excitation appears in the bulbar respiratory centre, its peripheral manifestation being powerful electrical activity of expiratory muscles (expiratory reflex) or of both expiratory and inspiratory muscles (coughing). Respiratory defensive reflexes are very powerful and stable and are retained in hypercapnia and hypoxia.

摘要

在21只戊巴比妥(40毫克/千克,腹腔注射)麻醉的雄性和雌性猫身上,通过立体定位法和肌电图法研究了延髓呼吸神经元的冲动活动以及主要呼吸肌的电活动,这些活动发生在防御性呼吸(呼气和咳嗽)反射过程中。在刺激喉咽和气管支气管感受器时,延髓呼吸中枢会出现明显的兴奋灶,其外周表现为呼气肌的强烈电活动(呼气反射)或呼气肌和吸气肌两者的强烈电活动(咳嗽)。呼吸防御反射非常强大且稳定,在高碳酸血症和低氧血症时仍会保留。

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