Seymour C B, Mothersill C, Moriarty M J, Tipton K F
Br J Radiol. 1987 Jun;60(714):577-81. doi: 10.1259/0007-1285-60-714-577.
The radiobiological response of CHO-K1 cells treated with ethanol is described. Both radioprotective and radiosensitising effects were found, depending on the duration of exposure before irradiation and the number of cells exposed. In spite of effects of ethanol on the shoulder of the primary survival curve, split-dose recovery was not affected. The radiobiological effect of alcohols is normally attributed either to radical scavenging or to oxidation. The findings presented here do not support either of these mechanisms.
描述了用乙醇处理的CHO-K1细胞的放射生物学反应。根据照射前暴露的持续时间和暴露的细胞数量，发现了放射防护和放射增敏两种效应。尽管乙醇对初始存活曲线的肩部有影响，但分次剂量恢复不受影响。醇类的放射生物学效应通常归因于自由基清除或氧化。此处给出的研究结果不支持这两种机制中的任何一种。
