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糖尿病患者的结直肠癌——流行病学、病理生理学及临床实践应用

[Colorectal cancer in patients with diabetes - epidemiology, pathophysiology and applications for clinical practice].

作者信息

Romanová Alexandra, Malinovská Jana, Lustigová Michala, Urbanová Jana, Brunerová Ludmila, Vejtasová Veronika, Verma Ankita, Duong Tung A, Šťovíček Jan, Brož Jan

出版信息

Vnitr Lek. 2022 Summer;68(2):116-122.

PMID:36208926
Abstract

Diabetes mellitus (type 2 diabetes in particular) and colorectal carcinoma are relatively frequent diseases in our population. At the same time, these units share some common risk factors, for example obesity, lack of physical activity and hyperinsulinemia. Available data show patients with diabetes have increased risk of colorectal adenoma and carcinoma, increased risk of colorectal carcinoma at a lower age, as well as increased risk of relapse and increased mortality with colorectal cancer. The aim of this article is to point out the relationship between diabetes and colorectal carcinoma, with emphasis on the information important for clinical practice, particularly the screening of colorectal carcinoma and lifestyle recommendations for patients with diabetes. Therefore, we offer an overview of the important available publications which consider this topic.

摘要

糖尿病(尤其是2型糖尿病)和结直肠癌在我们的人群中是相对常见的疾病。同时,这些疾病有一些共同的风险因素,例如肥胖、缺乏体育活动和高胰岛素血症。现有数据表明,糖尿病患者患结直肠腺瘤和癌的风险增加,在较低年龄患结直肠癌的风险增加,以及结直肠癌复发风险增加和死亡率增加。本文的目的是指出糖尿病与结直肠癌之间的关系,重点是对临床实践重要的信息,特别是结直肠癌的筛查和糖尿病患者的生活方式建议。因此,我们概述了有关此主题的重要现有出版物。

相似文献

1
[Colorectal cancer in patients with diabetes - epidemiology, pathophysiology and applications for clinical practice].糖尿病患者的结直肠癌——流行病学、病理生理学及临床实践应用
Vnitr Lek. 2022 Summer;68(2):116-122.
2
Type 2 diabetes mellitus as risk factor for colorectal cancer.2型糖尿病作为结直肠癌的危险因素。
Arch Physiol Biochem. 2008 Feb;114(1):84-98. doi: 10.1080/13813450802008455.
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Type 2 diabetes impacts colorectal adenoma detection in screening colonoscopy.2 型糖尿病影响筛查结肠镜检查中的结直肠腺瘤检出率。
Sci Rep. 2020 May 8;10(1):7793. doi: 10.1038/s41598-020-64344-2.
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New Horizons: Epidemiology of Obesity, Diabetes Mellitus, and Cancer Prognosis.新视野:肥胖症、糖尿病与癌症预后的流行病学
J Clin Endocrinol Metab. 2024 Mar 15;109(4):924-935. doi: 10.1210/clinem/dgad450.
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How significant is the association between metabolic syndrome and prevalence of colorectal neoplasia?代谢综合征与结直肠肿瘤患病率之间的关联有多显著?
World J Gastroenterol. 2016 Sep 28;22(36):8103-11. doi: 10.3748/wjg.v22.i36.8103.
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[Colorectal carcinoma screening in patients with type 2 diabetes mellitus].2型糖尿病患者的结直肠癌筛查
Z Gastroenterol. 2006 Nov;44(11):1153-65. doi: 10.1055/s-2006-927132.
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Relationship between type-2 diabetes and use of metformin with risk of colorectal adenoma in an American population receiving colonoscopy.美国接受结肠镜检查人群中 2 型糖尿病与二甲双胍使用与结直肠腺瘤风险的关系。
J Diabetes Complications. 2013 Sep-Oct;27(5):463-6. doi: 10.1016/j.jdiacomp.2013.04.010. Epub 2013 Jun 5.
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[Colorectal carcinoma and diabetes mellitus].
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Colorectal cancer outcomes, recurrence, and complications in persons with and without diabetes mellitus: a systematic review and meta-analysis.结直肠癌结局、复发和合并糖尿病与非糖尿病患者的比较:系统评价和荟萃分析。
Dig Dis Sci. 2010 Jul;55(7):1839-51. doi: 10.1007/s10620-009-0944-8.
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Type 2 diabetes mellitus: the impact on colorectal adenoma risk in women.
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引用本文的文献

1
A New Risk-Scoring System for Colorectal Cancer and Polyp Screening.一种用于结直肠癌和息肉筛查的新风险评分系统。
Turk J Gastroenterol. 2022 Dec;33(12):1079. doi: 10.5152/tjg.2022.22431.