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与严重 COVID-19 相关的获得性周围神经损伤的分布提示存在一种嵌压性神经病的机制:一种可穿戴、无线压力传感器的多中心病例系列和临床可行性研究。

The distribution of acquired peripheral nerve injuries associated with severe COVID-19 implicate a mechanism of entrapment neuropathy: a multicenter case series and clinical feasibility study of a wearable, wireless pressure sensor.

机构信息

Shirley Ryan Ability Lab, 26-North, 355 E. Erie Street, Chicago, IL, 60611, USA.

Department of Physical Medicine and Rehabilitation, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.

出版信息

J Neuroeng Rehabil. 2022 Oct 8;19(1):108. doi: 10.1186/s12984-022-01089-1.

DOI:10.1186/s12984-022-01089-1
PMID:36209094
原文链接:
https://pmc.ncbi.nlm.nih.gov/articles/PMC9547638/
Abstract

We diagnosed 66 peripheral nerve injuries in 34 patients who survived severe coronavirus disease 2019 (COVID-19). We combine this new data with published case series re-analyzed here (117 nerve injuries; 58 patients) to provide a comprehensive accounting of lesion sites. The most common are ulnar (25.1%), common fibular (15.8%), sciatic (13.1%), median (9.8%), brachial plexus (8.7%) and radial (8.2%) nerves at sites known to be vulnerable to mechanical loading. Protection of peripheral nerves should be prioritized in the care of COVID-19 patients. To this end, we report proof of concept data of the feasibility for a wearable, wireless pressure sensor to provide real time monitoring in the intensive care unit setting.

摘要

我们诊断了 34 名幸存严重 2019 冠状病毒病(COVID-19)患者中的 66 例周围神经损伤。我们将这些新数据与这里重新分析的已发表病例系列(117 例神经损伤;58 例患者)相结合,提供了病变部位的全面说明。最常见的是尺神经(25.1%)、腓总神经(15.8%)、坐骨神经(13.1%)、正中神经(9.8%)、臂丛神经(8.7%)和桡神经(8.2%),这些神经位于已知易受机械负荷影响的部位。在 COVID-19 患者的护理中,应优先保护周围神经。为此,我们报告了可穿戴式无线压力传感器实时监测重症监护病房环境的可行性的概念验证数据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2158/9548144/f1b498de8a79/12984_2022_1089_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2158/9548144/c64d5c938bac/12984_2022_1089_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2158/9548144/f1b498de8a79/12984_2022_1089_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2158/9548144/c64d5c938bac/12984_2022_1089_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2158/9548144/f1b498de8a79/12984_2022_1089_Fig2_HTML.jpg

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