Department for Pulmonology, Qitai Hospital of the Sixth Division of Xinjiang Production and Construction Corps, Qitai, China.
Genskey Medical Technology Co., Ltd, Beijing, China.
Int J Infect Dis. 2022 Nov;124:171-173. doi: 10.1016/j.ijid.2022.09.037. Epub 2022 Oct 6.
Chlamydia pecorum is a zoonotic pathogen. Here, we report the first case of human infection with C. pecorum. A man aged 51 years with high fever and dry cough was diagnosed with severe community-acquired pneumonia and respiratory failure. C. pecorum was found responsible for the infection, which was detected from bronchoalveolar lavage fluid through metagenomic next-generation sequencing. C. pecorum infection was further identified by quantitative polymerase chain reaction and complement fixation test. The patient's condition improved rapidly after targeted treatment. He was a farmer with diabetes mellitus and had a history of close contact with sheep, which might result in C. pecorum infection. Our report could provide a direction for the diagnosis and treatment of human C. pecorum pneumonia.
绵羊衣原体是人畜共患病原体。本研究报告了首例人类感染绵羊衣原体的病例。一名 51 岁男性，因高热和干咳被诊断为重症社区获得性肺炎和呼吸衰竭。通过宏基因组下一代测序从支气管肺泡灌洗液中发现该患者感染了绵羊衣原体。通过定量聚合酶链反应和补体结合试验进一步鉴定了绵羊衣原体感染。针对性治疗后，患者病情迅速改善。该患者是一名农民，患有糖尿病，有与绵羊密切接触的病史，这可能导致了绵羊衣原体感染。本研究为人类衣原体肺炎的诊断和治疗提供了方向。
