Tan Y K, Ling A E, Lin R V, Ong Y Y, Wong S Y
Department of Respiratory and Critical Care Medicine, Singapore General Hospital.
Ann Acad Med Singap. 1995 Nov;24(6):863-6.
Chlamydia pneumoniae, previously known as Chlamydia psittaci strain TWAR, causes both upper and lower respiratory tract infection. We report the first two cases of culture-positive Chlamydia pneumoniae lower respiratory infection in Singapore. Both patients had underlying fibrosing alveolitis and presented with a history of prolonged productive cough and fever. Chlamydia pneumoniae was isolated from the bronchoalveolar lavage fluid in the absence of other pathogens. The patients responded clinically to three weeks of oral doxycycline therapy. Infection due to Chlamydia pneumoniae should be considered when a patient with community-acquired pneumonia fails to respond to the usual standard antimicrobial therapy.
肺炎衣原体，以前称为鹦鹉热衣原体TWAR株，可引起上、下呼吸道感染。我们报告了新加坡首例两例培养阳性的肺炎衣原体下呼吸道感染病例。两名患者均患有潜在的纤维化肺泡炎，均有长期咳痰和发热病史。在未发现其他病原体的情况下，从支气管肺泡灌洗液中分离出肺炎衣原体。患者对三周的口服强力霉素治疗有临床反应。当社区获得性肺炎患者对常规标准抗菌治疗无反应时，应考虑肺炎衣原体感染。
