Department of Surgical Oncology, Faculty of Medicine, Saglik Bilimleri University, Adana City Training & Research Hospital, Adana, Turkey.
Department of Pathology, Faculty of Medicine, Saglik Bilimleri University, Adana City Training & Research Hospital, Adana, Turkey.
J Coll Physicians Surg Pak. 2022 Aug;32(8):S92-S94. doi: 10.29271/jcpsp.2022.Supp2.S92.
Phyllodes tumours are uncommon breast neoplasms constituting 1-2% of breast malignancies. Metastasis is usually haematogenous, and axillary lymph node dissection is not routinely performed. A phyllodes tumour with concomitant invasive ductal carcinoma (IDC) is even rarer. When IDCor ductal carcinoma in-situ (DCIS) is detected, the management of the condition changes completely. We report a case of a 22-year female presenting with a mass in the right breast and palpable axillary lymph nodes. The pathological examination demonstrated a malignant phyllodes tumour with concomitant IDC and DCIS. The patient elected to have modified radical mastectomy, and the pathological examination showed metastasis in the axillary lymph nodes. The patient was administered appropriate therapy. At the last visit, she did not have the clinical signs of disease. This is the first youngest case of axillary lymph node metastases with both DCIS and IDC on pathological examination in malignant phyllodes tumour. Key Words: Malignant phyllodes, Invasive ductal carcinoma, Ductal carcinoma in-situ, Lymph node metastasis.
叶状肿瘤是一种罕见的乳腺肿瘤，占乳腺恶性肿瘤的 1-2%。转移通常是血行性的，通常不常规进行腋窝淋巴结清扫。同时伴有浸润性导管癌（IDC）的叶状肿瘤则更为罕见。当检测到 IDC 或导管原位癌（DCIS）时，疾病的治疗方法会完全改变。我们报告了一例 22 岁女性，右侧乳房有肿块，可触及腋窝淋巴结。病理检查显示为恶性叶状肿瘤，伴有 IDC 和 DCIS。患者选择接受改良根治性乳房切除术，病理检查显示腋窝淋巴结转移。患者接受了适当的治疗。最后一次就诊时，她没有疾病的临床迹象。这是首例在恶性叶状肿瘤中，病理检查同时发现 DCIS 和 IDC 的最年轻腋窝淋巴结转移病例。
恶性叶状肿瘤、浸润性导管癌、导管原位癌、淋巴结转移。
