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患者以味觉障碍就诊时的孤立性浆细胞瘤。

Solitary Plasmacytoma in a Patient Presenting with Taste Disturbance.

机构信息

Department of Internal Medicine, Faculty of Medicine, Balikesir University, Balikesir, Turkey.

Department of Internal Medicine, Endocrinology and Metabolic Diseases, Faculty of Medicine, Balikesir University, Balikesir, Turkey.

出版信息

J Coll Physicians Surg Pak. 2022 Aug;32(8):S165-S167. doi: 10.29271/jcpsp.2022.Supp2.S165.

DOI:10.29271/jcpsp.2022.Supp2.S165
PMID:36210683
Abstract

Solitary plasmacytoma is a disease included in plasma cell dyscrasias, presenting outside of the bone marrow, and with the potential to turn into multiple myeloma. A 66-year male patient was admitted to the hematology clinic with the complaint of impaired taste. Physical examination revealed edema of the left pharynx. After excisional tissue biopsy, serum/urine protein electrophoresis, and immunofixation tests of the patient diagnosed with plasmacytoma were negative. An increase in atypical plasma cells was noted on bone marrow aspiration and biopsy. There was no systemic involvement outside the pharynx on the PET-CT examination. He was referred to the radiotherapy department for further management. Since the affected area is frequently the nasopharynx, sinuses, and larynx in extramedullary solitary plasmacytoma cases, they generally presented to the clinic with difficulty in swallowing, shortness of breath and pain symptoms. This case presented with a non-specific complaint of taste disturbance along with difficulty in swallowing. Key Words: Plasmacytoma, Nasopharynx, Multiple myeloma.

摘要

孤立性浆细胞瘤是一种浆细胞疾病,发生在骨髓外,有可能发展为多发性骨髓瘤。一名 66 岁男性患者因味觉障碍到血液科就诊。体格检查发现左咽部水肿。对患者进行组织活检、血清/尿液蛋白电泳和免疫固定试验后,诊断为浆细胞瘤。骨髓抽吸和活检显示异常浆细胞增多。PET-CT 检查未发现咽外全身受累。他被转介到放射治疗科进一步治疗。由于骨髓外孤立性浆细胞瘤常发生于鼻咽、鼻窦和喉部,因此患者常因吞咽困难、呼吸困难和疼痛等症状就诊。本例患者表现为非特异性味觉障碍伴吞咽困难。

关键词

浆细胞瘤、鼻咽、多发性骨髓瘤。

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