Berard Meredyth B, Lau Frank H
School of Medicine Louisiana State University Health Sciences Center New Orleans Louisiana USA.
Division of Plastic and Reconstructive Surgery, Department of Surgery Louisiana State University Health Sciences Center New Orleans Louisiana USA.
Health Sci Rep. 2022 Oct 3;5(6):e865. doi: 10.1002/hsr2.865. eCollection 2022 Nov.
Minimally adherent silver dressings (SILVER MASD) are antimicrobial, nonirritating, provide a moist wound healing environment, and low cost. The purpose of this pilot, single-center, non-blinded randomized controlled trial was to quantify the outcomes of acute surgical wounds treated with MASD versus standard of care (SoC) dressings.
Thirty-two patients with acute wounds were randomized 1:1 to be treated with MASD once weekly or SoC following surgical excision of skin and/or subcutaneous tissue between September 13, 2016 and November 28, 2017. The outcome variables included clinical infection, time to wound closure, and pain scores at dressing changes. Two independent, one-sided sample -tests were performed to assess statistical significance.
There was no difference in wound healing between SILVER MASD and SoC. Dressing changes were less painful for wounds managed with MASD silver dressings.
The results of this study suggest that MASD are not less effective in wound healing compared to SoC while also providing the benefit of decreased pain at dressing changes. Therefore, minimally adherent silver dressings can and should be considered a viable option in the management of acute surgical wounds.
微粘性银敷料（SILVER MASD）具有抗菌、无刺激性，能提供湿润的伤口愈合环境且成本低廉的特点。本单中心、非盲法的随机对照试验旨在量化采用MASD敷料与标准护理（SoC）敷料治疗急性手术伤口的效果。
2016年9月13日至2017年11月28日期间，32例急性伤口患者按1:1随机分组，在手术切除皮肤和/或皮下组织后，一组每周使用一次MASD敷料，另一组采用标准护理敷料。观察指标包括临床感染、伤口愈合时间以及换药时的疼痛评分。采用两个独立的单侧样本检验评估统计学意义。
SILVER MASD敷料与标准护理敷料在伤口愈合方面无差异。使用MASD银敷料处理的伤口换药时疼痛较轻。
本研究结果表明，与标准护理相比，MASD在伤口愈合方面效果不逊色，同时还具有换药时疼痛减轻的优势。因此，微粘性银敷料可以且应该被视为急性手术伤口处理中的一个可行选择。
