Larson D M, Copeland L J, Gallager H S, Wharton J T, Gershenson D M, Edwards C L, Malone J M, Rutledge F N
Cancer. 1987 Sep 15;60(6):1358-61. doi: 10.1002/1097-0142(19870915)60:6<1358::aid-cncr2820600633>3.0.co;2-o.
The rarity of Stage II endometrial carcinoma and variable treatment modalities have made the evaluation of prognostic factors difficult. Clinical, surgical, and pathologic characteristics were evaluated in 64 patients treated with whole pelvic irradiation and intracavitary radium followed by hysterectomy at The University of Texas M.D. Anderson Hospital and Tumor Institute from January 1965 to December 1983. Comparison of 5-year actuarial survival rates revealed the following statistically significant categories: age, grade, depth of myometrial invasion, disease extent at surgery including lymph node metastases, and pelvic cytology. Race, weight, and cell type were not significant prognostic factors. Evaluation of prognostic factors at surgery includes pelvic and para-aortic lymph node biopsies, omental biopsy, pelvic cytologic washings, and biopsy of any suspicious tissues. Patients with adverse prognostic factors are candidates for trials with adjuvant therapy.
II期子宫内膜癌的罕见性以及多样的治疗方式使得评估预后因素变得困难。1965年1月至1983年12月期间，在德克萨斯大学MD安德森医院和肿瘤研究所，对64例接受全盆腔照射和腔内镭疗后再行子宫切除术的患者的临床、手术和病理特征进行了评估。5年精算生存率的比较显示出以下具有统计学意义的类别：年龄、分级、肌层浸润深度、手术时的疾病范围（包括淋巴结转移）以及盆腔细胞学检查。种族、体重和细胞类型不是显著的预后因素。手术时对预后因素的评估包括盆腔和腹主动脉旁淋巴结活检、大网膜活检、盆腔细胞学冲洗以及对任何可疑组织的活检。具有不良预后因素的患者是辅助治疗试验的候选对象。
