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超声能否作为诊断抗N-甲基-D-天冬氨酸受体脑炎的诊断方式?

Can ultrasound be the diagnostic modality to diagnosis anti-N-methyl-D-aspartate receptor encephalitis?

作者信息

Alaya Andrew, van Dunné Frédérique

机构信息

Gynaecology and Obstetrics Department, Haaglanden Medisch Centrum, The Hague, The Netherlands.

出版信息

BJR Case Rep. 2022 Sep 12;8(5):20220024. doi: 10.1259/bjrcr.20220024.

Abstract

Anti-N-methyl-D-aspartate receptor encephalitis is an auto-immune paraneoplastic disease of the limbic system. This syndrome may present itself as a range of psychiatric, neurological and autonomic features. It is associated with long-term morbidity and mortality. The syndrome is associated with ovarian teratoma affecting mainly young females. If the syndrome is identified at an early stage, then a good prognosis is expected. In this case report, the ultrasound performed by an experienced and competent operator was more sensitive than MRI in diagnosing a small ovarian teratoma. Following the removal of the teratoma and with appropriate immunotherapy the patient's condition improved. In the clinical suspicion of anti-A-methyl-D-aspartate receptor encephalitis, the first modality of choice should be an ultrasound of the ovaria performed by an experienced and competent operator.

摘要

抗N-甲基-D-天冬氨酸受体脑炎是一种边缘系统的自身免疫性副肿瘤性疾病。该综合征可能表现为一系列精神、神经和自主神经特征。它与长期的发病率和死亡率相关。该综合征与主要影响年轻女性的卵巢畸胎瘤有关。如果在早期识别出该综合征,则预后良好。在本病例报告中,由经验丰富且技术熟练的操作人员进行的超声检查在诊断小卵巢畸胎瘤方面比MRI更敏感。切除畸胎瘤并进行适当的免疫治疗后,患者的病情有所改善。在临床怀疑抗N-甲基-D-天冬氨酸受体脑炎时,首选的检查方式应由经验丰富且技术熟练的操作人员对卵巢进行超声检查。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab4c/9518731/9b85a882ea4f/bjrcr.20220024.g001.jpg

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