Panchal Shital S, Mishra Umang, Kothari Charmy, Kothari Vijay, Dalai Sarat, Mecwan Marcellin, Chaudhary Shrishma, Sharma Juhi, Shah Priyanka
Institute of Pharmacy, Nirma University, Sarkhej-Gandhinagar Highway, Ahmedabad, Gujarat, India.
Epidemic Branch, Commissionerate of Health, Medical Services and Medical Education (HS), Govt. of Gujarat, Gandhinagar, Gujarat, India.
J Taibah Univ Med Sci. 2022 May 29;17(6):1087-1093. doi: 10.1016/j.jtumed.2022.05.002. eCollection 2022 Dec.
Anemia is a global health problem and has very high prevalence in developing as well as developed countries, particularly in children and women. The present study evaluates hematological predictors, nutrition deficiency, parasitic infections and their association with the prevalence of anemia. This analysis will help to identify the anemic status of tribal preschool children.
This was a cross-sectional study conducted in 300 children (age: 6 months to 5 years) in Santrampur village, Gujarat. Blood was collected and used to determine complete blood count (CBC); we also performed ELISA (enzyme-linked immunoassay) for the estimation of ferritin, transferrin, sTfR (soluble transferrin receptor), vitamin B and vitamin B (folate). Stool samples were also collected and assessed by ELISA for and Microscopy was used to screen samples for malaria.
Of the 300 children analyzed, 87.7% were anemic, 239 children were mildly anemic, 20 were moderately anemic and 4 were severely anemic. Mean Hb level was 9.49 ± 1.47 g/dL; males and females had an Hb level of 9.39 ± 1.59 g/dL and 9.58 ± 1.34 g/dL, respectively. Twenty-six children had sickle cell anemia and five had thalassemia. Over 50% of the children had vitamin B and B deficiency and 16% had abnormalities in CRP (C-reactive protein) levels. Parasitic infection by was positively associated the anemia followed by the prevalence of and .
An increased awareness of parents in the improvement of sanitary facilities and nutritional counselling with regards to iron-rich food consumption is recommended to if we are to prevent anemia among pre-school children. To reduce parasitic infestation, effective periodic deworming measures are also recommended.
贫血是一个全球性的健康问题，在发展中国家和发达国家都有很高的患病率，尤其是在儿童和妇女中。本研究评估血液学预测指标、营养缺乏、寄生虫感染及其与贫血患病率的关联。该分析将有助于确定部落学龄前儿童的贫血状况。
这是一项在古吉拉特邦桑特拉姆布尔村对300名儿童（年龄：6个月至5岁）进行的横断面研究。采集血液用于测定全血细胞计数（CBC）；我们还进行了酶联免疫吸附测定（ELISA）以评估铁蛋白、转铁蛋白、可溶性转铁蛋白受体（sTfR）、维生素B和维生素B（叶酸）。还采集了粪便样本，并通过ELISA检测 和 。显微镜检查用于筛查疟疾样本。
在分析的300名儿童中，87.7%患有贫血，239名儿童轻度贫血，20名儿童中度贫血，4名儿童重度贫血。平均血红蛋白水平为9.49±1.47g/dL；男性和女性的血红蛋白水平分别为9.39±1.59g/dL和9.58±1.34g/dL。26名儿童患有镰状细胞贫血，5名儿童患有地中海贫血。超过50%的儿童存在维生素B和B缺乏，16%的儿童C反应蛋白（CRP）水平异常。 的寄生虫感染与贫血呈正相关，其次是 和 的患病率。
如果我们要预防学龄前儿童贫血，建议提高家长对改善卫生设施和关于食用富含铁的食物的营养咨询的认识。为减少寄生虫感染，还建议采取有效的定期驱虫措施。
