Lugo-Fagundo Elias, Lugo-Fagundo Carolina, Weisberg Edmund M, Fishman Elliot K
Johns Hopkins Medicine, The Russell H. Morgan Department of Radiology and Radiological Science, 601 North Caroline St, Baltimore, MD 21287, USA.
Radiol Case Rep. 2022 Oct 3;17(12):4727-4729. doi: 10.1016/j.radcr.2022.09.035. eCollection 2022 Dec.
Rhabdomyolysis is distinguished by the breakdown of skeletal muscle and the subsequent release of intracellular components into the bloodstream. Necrosis, which commonly manifests as muscle swelling, weakness, and myalgia, is a symptom associated with both traumatic and non-traumatic rhabdomyolysis. The etiology may be considered acquired, including trauma, infections, and drugs, or genetic, such as myopathies or enzyme deficiencies. Diagnosed by exceedingly high creatine kinase levels, rhabdomyolysis can lead to increased serum levels or more worrisome complications such as life-threatening acute kidney injury. In this article, we report the case of a 56-year-old male with a diagnosis of severe rhabdomyolysis and acute renal failure. We focus on optimizing diagnosis through the application of radiological modalities.
横纹肌溶解症的特征是骨骼肌分解,随后细胞内成分释放到血液中。坏死通常表现为肌肉肿胀、无力和肌痛,是创伤性和非创伤性横纹肌溶解症的相关症状。病因可分为后天性,包括创伤、感染和药物,或遗传性,如肌病或酶缺乏。横纹肌溶解症通过极高的肌酸激酶水平诊断,可导致血清水平升高或更令人担忧的并发症,如危及生命的急性肾损伤。在本文中,我们报告了一例诊断为严重横纹肌溶解症和急性肾衰竭的56岁男性病例。我们专注于通过应用放射学检查方法优化诊断。