影响鼻窦恶性肿瘤诊断和预后的因素。
Factors Contributing to Diagnosis and Prognosis in Sinonasal Malignancies.
机构信息
E.N.T. Department, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu 213000, China.
出版信息
J Immunol Res. 2022 Sep 29;2022:4406838. doi: 10.1155/2022/4406838. eCollection 2022.
OBJECTIVES
This study was intended to explore and analyze the factors which affect the survival and prognosis of patients with malignant tumors of nasal cavity and sinus.
METHODS
Retrospective analysis was performed on the clinical data of 39 cases of malignant tumors of nasal cavity and sinus that met the requirements of the study. A follow-up study was performed on the patients for more than 36 months. Survival analysis was conducted via the Kaplan-Meier method and log-rank test. Cox regression model was used for multivariate analysis.
RESULTS
Gender, pathological type, treatment plan, clinical stage, and survival time of patients were different. Clinical stage was substantially related to the survival of patients ( < 0.05), which was an independent factor affecting prognosis.
CONCLUSIONS
Early detection and comprehensive treatment of sinonasal malignancies can improve the prognosis and prolong the survival time of patients.
目的
本研究旨在探讨和分析影响鼻腔鼻窦恶性肿瘤患者生存和预后的因素。
方法
对符合研究要求的 39 例鼻腔鼻窦恶性肿瘤患者的临床资料进行回顾性分析，对患者进行超过 36 个月的随访，采用 Kaplan-Meier 法和 log-rank 检验进行生存分析，Cox 回归模型进行多因素分析。
结果
患者的性别、病理类型、治疗方案、临床分期和生存时间不同，临床分期与患者的生存有显著相关性（<0.05），是影响预后的独立因素。
结论
早期发现和综合治疗鼻腔鼻窦恶性肿瘤可以改善患者的预后，延长患者的生存时间。
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