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Meta 分析下直肠低位 经腹会阴联合切除联合选择性侧方淋巴结清扫的疗效及安全性

Efficacy and Safety of Radical Resection of Rectal Combined with Selective Lateral Lymph Node Dissection in the Treatment of Low Rectal under Meta-analysis.

机构信息

Department of Gastrointestinal Surgery, Hunan Provincial People's Hospital (the First Affiliated Hospital of Hunan Normal University), Changsha 410005, China.

出版信息

Contrast Media Mol Imaging. 2022 Sep 21;2022:8456677. doi: 10.1155/2022/8456677. eCollection 2022.

Abstract

Rectal cancer mostly occurs in the middle and low position in China, and many anatomical evidence has confirmed that Lateral Lymph Node Metastasis (LLNM) exists in middle and low rectal cancer. Laparoscopic surgery can penetrate into the pelvic cavity and magnify and narrow the visual field, which is helpful for lymph node dissection and vascular nerve protection, while it has minimally invasive characteristics and is considered to be more suitable for LLND. Relevant articles published from January 2000 to May 2022 are searched using "Rectal cancer, Lateral lymph node dissection, Radical resection of rectal cancer, Low rectal cancer, Laparoscopic therapy, Treatment of rectal cancer" as test terms, analyzed and assessed using Rev Man 5.3 software and Stata software to assess the risk bias of included references, and heterogeneity among each study is evaluated using test and heterogeneity (I2). The experimental results show that there is no heterogeneity among the studies (I2 = 8.46%). The heterogeneity of lymphatic metastasis in the included literature is evaluated, and the results show that there is heterogeneity between the studies (I2 = 52.06%).

摘要

直肠癌主要发生在中国的中低位,许多解剖学证据已经证实中低位直肠癌存在侧方淋巴结转移(LLNM)。腹腔镜手术可以进入盆腔,放大并缩小视野,有利于淋巴结清扫和血管神经保护,同时具有微创的特点,被认为更适合 LLND。检索 2000 年 1 月至 2022 年 5 月期间以“直肠癌、侧方淋巴结清扫、直肠癌根治术、低位直肠癌、腹腔镜治疗、直肠癌治疗”为检索词的相关文章,采用 Rev Man 5.3 软件和 Stata 软件进行分析和评估纳入参考文献的风险偏倚,并采用卡方检验和异质性(I2)评估各研究之间的异质性。实验结果表明,研究之间没有异质性(I2=8.46%)。评估纳入文献中淋巴转移的异质性,结果显示研究之间存在异质性(I2=52.06%)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c399/9519300/c580c494cc25/CMMI2022-8456677.001.jpg

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