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类固醇难治性登革热肌炎对静脉注射免疫球蛋白有反应的病例。

Case of steroid refractory dengue myositis responsive to intravenous immunoglobulins.

机构信息

Internal Medicine, Hayatabad Medical Complex, Peshawar, Pakistan.

Neuroimmunology Division, Yale School of Medicine, New Haven, Connecticut, USA

出版信息

BMJ Case Rep. 2022 Oct 10;15(10):e250963. doi: 10.1136/bcr-2022-250963.

Abstract

Dengue is an arbovirus infection that usually presents with the symptoms of high-grade fever, myalgia and rash. Dengue is spread by the mosquito and frequent outbreaks are being reported in regions like Pakistan, India and Sri Lanka. Although muscle ache is quite common with dengue fever, overt myositis is of very rare occurrence. Here, we report a case of a young girl who presented to us with serologically confirmed dengue infection, and having bilateral upper and lower limb weakness. Her raised creatine kinase, along with her electromyography pattern was suggestive of myositis. Her condition was steroid-resistant and responded only to intravenous immunoglobulin. She was discharged in a stable condition.

摘要

登革热是一种虫媒病毒感染,通常表现为高热、肌痛和皮疹。登革热由蚊子传播,巴基斯坦、印度和斯里兰卡等地区经常爆发登革热。虽然肌肉疼痛在登革热中很常见,但明显的肌炎非常罕见。在这里,我们报告了一例年轻女孩的病例,她因血清学确诊的登革热感染,出现双侧上下肢无力。她的肌酸激酶升高,以及她的肌电图模式提示肌炎。她的病情对类固醇耐药,仅对静脉注射免疫球蛋白有反应。她出院时情况稳定。

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本文引用的文献

1
Dengue fever presenting with severe myositis-An unusual presentation.登革热伴严重肌炎——一种不寻常的表现。
J Family Med Prim Care. 2020 Dec 31;9(12):6285-6287. doi: 10.4103/jfmpc.jfmpc_1680_20. eCollection 2020 Dec.
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Neurological Manifestations of Dengue Infection.登革热感染的神经表现。
Front Cell Infect Microbiol. 2017 Oct 25;7:449. doi: 10.3389/fcimb.2017.00449. eCollection 2017.
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Dengue-associated neuromuscular complications.登革热相关的神经肌肉并发症。
Neurol India. 2015 Jul-Aug;63(4):497-516. doi: 10.4103/0028-3886.161990.
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Corticosteroids for dengue infection.用于登革热感染的皮质类固醇。
Cochrane Database Syst Rev. 2014 Jul 1;2014(7):CD003488. doi: 10.1002/14651858.CD003488.pub3.
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Dengue encephalitis.登革热脑炎
Indian J Crit Care Med. 2011 Jul;15(3):190-3. doi: 10.4103/0972-5229.84896.

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