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类固醇难治性登革热肌炎对静脉注射免疫球蛋白有反应的病例。

Case of steroid refractory dengue myositis responsive to intravenous immunoglobulins.

机构信息

Internal Medicine, Hayatabad Medical Complex, Peshawar, Pakistan.

Neuroimmunology Division, Yale School of Medicine, New Haven, Connecticut, USA

出版信息

BMJ Case Rep. 2022 Oct 10;15(10):e250963. doi: 10.1136/bcr-2022-250963.

DOI:10.1136/bcr-2022-250963
PMID:36216376
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9557321/
Abstract

Dengue is an arbovirus infection that usually presents with the symptoms of high-grade fever, myalgia and rash. Dengue is spread by the mosquito and frequent outbreaks are being reported in regions like Pakistan, India and Sri Lanka. Although muscle ache is quite common with dengue fever, overt myositis is of very rare occurrence. Here, we report a case of a young girl who presented to us with serologically confirmed dengue infection, and having bilateral upper and lower limb weakness. Her raised creatine kinase, along with her electromyography pattern was suggestive of myositis. Her condition was steroid-resistant and responded only to intravenous immunoglobulin. She was discharged in a stable condition.

摘要

登革热是一种虫媒病毒感染,通常表现为高热、肌痛和皮疹。登革热由蚊子传播,巴基斯坦、印度和斯里兰卡等地区经常爆发登革热。虽然肌肉疼痛在登革热中很常见,但明显的肌炎非常罕见。在这里,我们报告了一例年轻女孩的病例,她因血清学确诊的登革热感染,出现双侧上下肢无力。她的肌酸激酶升高,以及她的肌电图模式提示肌炎。她的病情对类固醇耐药,仅对静脉注射免疫球蛋白有反应。她出院时情况稳定。

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Case of steroid refractory dengue myositis responsive to intravenous immunoglobulins.类固醇难治性登革热肌炎对静脉注射免疫球蛋白有反应的病例。
BMJ Case Rep. 2022 Oct 10;15(10):e250963. doi: 10.1136/bcr-2022-250963.
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本文引用的文献

1
Dengue fever presenting with severe myositis-An unusual presentation.登革热伴严重肌炎——一种不寻常的表现。
J Family Med Prim Care. 2020 Dec 31;9(12):6285-6287. doi: 10.4103/jfmpc.jfmpc_1680_20. eCollection 2020 Dec.
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Arboviruses and Muscle Disorders: From Disease to Cell Biology.虫媒病毒与肌肉疾病:从疾病到细胞生物学。
Viruses. 2020 Jun 5;12(6):616. doi: 10.3390/v12060616.
3
Concurrent Guillain-Barré syndrome and myositis complicating dengue fever.并发吉兰-巴雷综合征和肌炎的登革热并发症
BMJ Case Rep. 2020 Feb 10;13(2):e232940. doi: 10.1136/bcr-2019-232940.
4
Effectiveness of corticosteroid in the treatment of dengue - A systemic review.皮质类固醇治疗登革热的有效性——一项系统评价。
Heliyon. 2018 Sep 22;4(9):e00816. doi: 10.1016/j.heliyon.2018.e00816. eCollection 2018 Sep.
5
Neurological Manifestations of Dengue Infection.登革热感染的神经表现。
Front Cell Infect Microbiol. 2017 Oct 25;7:449. doi: 10.3389/fcimb.2017.00449. eCollection 2017.
6
Dengue-associated neuromuscular complications.登革热相关的神经肌肉并发症。
Neurol India. 2015 Jul-Aug;63(4):497-516. doi: 10.4103/0028-3886.161990.
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Acute renal failure due to Dengue myositis: a rare cause of pigment cast nephropathy.登革热肌炎所致急性肾衰竭:色素管型肾病的罕见病因。
Clin Kidney J. 2013 Dec;6(6):662-3. doi: 10.1093/ckj/sft119.
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Corticosteroids for dengue infection.用于登革热感染的皮质类固醇。
Cochrane Database Syst Rev. 2014 Jul 1;2014(7):CD003488. doi: 10.1002/14651858.CD003488.pub3.
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A case presentation of a fatal dengue myocarditis showing evidence for dengue virus-induced lesion.一例致命性登革热心肌炎病例呈现登革病毒诱导损伤的证据。
Eur Heart J Acute Cardiovasc Care. 2013 Jun;2(2):127-30. doi: 10.1177/2048872613475889.
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Dengue encephalitis.登革热脑炎
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