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结节-溃疡性梅毒——病例报告及文献复习。

Nodulo-ulcerative syphilis - case report and the review of literature.

机构信息

Department of Dermatology and Venerology, Medical University of Białystok, Poland

Department of Medical Pathomorphology, Medical University of Białystok, Poland

出版信息

Przegl Epidemiol. 2022;76(2):184-189. doi: 10.32394/pe.76.18.

DOI:10.32394/pe.76.18
PMID:36217907
Abstract

We describe the case of tertiary syphilis involving the skin. The lesions had a nodular-ulcerative form, localized on both arms. The patient had high titers of treponemal and non-treponemal serological tests for syphilis and histopathological picture was indicative for nodulo-ulcerative syphilis. No cardiological, neurological or ophtalmological abnormalities were found. The patient was treated with 2.4 million units i.m. of benzathine benzylpenicillin three times at weekly intervals, according to European Guideline. Unfortunately, the patient was lost for scheduled follow-up. More than two years later the skin lesions healed completely leaving discrete scars and a four-fold decline in a titre of Venereal Disease Laboratory Test was noticed.

摘要

我们描述了一例累及皮肤的三期梅毒病例。病变呈结节-溃疡性,局限于双臂。患者梅毒螺旋体和非梅毒螺旋体血清学检测滴度均较高,组织病理学表现提示为结节-溃疡性梅毒。未发现心血管、神经或眼科异常。根据欧洲指南,患者接受了 240 万单位苄星青霉素肌内注射,每周三次,共三次。不幸的是,患者未能按计划进行随访。两年多后,皮肤病变完全愈合,留下离散的疤痕,梅毒血清学试验滴度下降了四倍。

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