硝基呋喃衍生物糠基糠酰胺（AF-2）诱导酿酒酵母中的基因转换。
Induction of gene conversion in Saccharomyces cerevisiae by the nitrofuran derivative furylfuramide (AF-2).
作者信息
Murthy M S, Sankaranarayanan N
出版信息
Mutat Res. 1978 Sep;58(1):99-101. doi: 10.1016/0165-1218(78)90099-x.
PMID:362196
Abstract
The nitrofuran derivative furylfuramide (AF-2) is known to be both mutagenic and carcinogenic in a number of test systems. In this report we show that AF-2 can also induce gene conversion in diploid yeast in a manner dependent on both duration and concentration of treatment.
摘要
已知呋喃类衍生物糠基糠酰胺（AF - 2）在许多测试系统中具有致突变性和致癌性。在本报告中，我们表明AF - 2还能以一种依赖于处理持续时间和浓度的方式在二倍体酵母中诱导基因转换。
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