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眼眶内容剜除术及近距离放射治疗用于治疗儿童、融合阳性、复发性横纹肌肉瘤

Orbital Exenteration and Brachytherapy for the Treatment of Pediatric, Fusion-positive, Recurrent Rhabdomyosarcoma.

作者信息

Lopez Joseph, Qin Nancy, Woods Robbie, Golden Marjorie, Spatz Harrison, Shah Jatin, Wexler Leonard H, Randazzo Joseph, Wolden Suzanne L, Abramson David H

机构信息

Department of Surgery, Head and Neck Service, Memorial Sloan Kettering Cancer Center, New York, N.Y.

Department of Surgery, Dental Service, Memorial Sloan Kettering Cancer Center, New York, N.Y.

出版信息

Plast Reconstr Surg Glob Open. 2022 Oct 7;10(10):e4581. doi: 10.1097/GOX.0000000000004581. eCollection 2022 Oct.

Abstract

A 20-month-old boy presented with biopsy-proven recurrent alveolar rhabdomyosarcoma without metastasis. He was previously treated with multiagent chemotherapy and external beam irradiation showing a complete response. Upon relapse, he was treated with chemotherapy, orbital exenteration, and brachytherapy. Customized, intraoperative brachytherapy has potential to limit the sequelae associated with radiation adjuvant therapy.

摘要

一名20个月大的男孩被诊断为经活检证实的复发性肺泡横纹肌肉瘤,无转移。他之前接受了多药化疗和外照射放疗,显示完全缓解。复发后,他接受了化疗、眼眶内容剜除术和近距离放射治疗。定制的术中近距离放射治疗有可能限制与放射辅助治疗相关的后遗症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3832/9543036/cccdade8b03f/gox-10-e4581-g001.jpg

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