Kennedy Krieger Institute, Center for Autism and Related Disorders, Baltimore, MD, US.
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, US.
J Autism Dev Disord. 2024 Jan;54(1):121-130. doi: 10.1007/s10803-022-05744-3. Epub 2022 Oct 13.
Intolerance of uncertainty (IU) is a multidimensional construct involving maladaptive responses to uncertainty. IU is strongly associated with autism and anxiety, yet no studies have examined its symptom profile in autistic children. This study compares IU symptom profiles in autistic and NT children and in autistic children with and without anxiety using the Intolerance of Uncertainty Scale for Children. Compared to NT peers, autistic children exhibited heightened IU symptoms in all domains, affective, behavioral, and cognitive; affective symptoms had the highest association with autism. Autistic children with anxiety also exhibited elevated IU symptoms in all domains compared to those without anxiety; behavioral IU symptoms had the highest association with anxiety. IU symptom profiles should be considered in assessment and treatment.
不确定性容忍度（IU）是一个多维结构，涉及对不确定性的适应不良反应。IU 与自闭症和焦虑症密切相关，但尚无研究检查其在自闭症儿童中的症状特征。本研究使用儿童不确定性容忍度量表比较了自闭症和 NT 儿童以及自闭症伴或不伴焦虑儿童的 IU 症状特征。与 NT 同龄人相比，自闭症儿童在所有领域（情感、行为和认知）都表现出更高的 IU 症状；情感症状与自闭症的关联度最高。与无焦虑的自闭症儿童相比，伴有焦虑的自闭症儿童在所有领域也表现出更高的 IU 症状；行为 IU 症状与焦虑的关联度最高。在评估和治疗中应考虑 IU 症状特征。
