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[维生素A和卡介苗对Lewis肺癌小鼠肿瘤生长和转移的抑制作用]

[Inhibition of tumor growth and metastases in mice with Lewis lung tumors by vitamin A and BCG].

作者信息

Kurata T, Micksche M

出版信息

Onkologie. 1978 Feb;1(1):16-9. doi: 10.1159/000213904.

Abstract

The anti-tumor effect of vitamin A and/or BCG was investigated in Lewis lung tumor system. Tumor growth and lung metastases were significantly suppressed, when tumor cells were mixed with BCG and inoculated subcutaneously into vitamin A-treated animals. Survival time was also prolonged by the same treatment. Vitamin A alone, without BCG, showed no effect on tumor growth, lung metastases or survival time.

摘要

在Lewis肺癌系统中研究了维生素A和/或卡介苗(BCG)的抗肿瘤作用。当将肿瘤细胞与卡介苗混合并皮下接种到经维生素A处理的动物体内时,肿瘤生长和肺转移得到显著抑制。相同的处理也延长了存活时间。单独使用维生素A,而不使用卡介苗,对肿瘤生长、肺转移或存活时间均无影响。

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