Department of Physiology, University of California, San Francisco, N412C Genentech Hall, 600 16th Street, San Francisco, CA 94143, USA.
Cell Host Microbe. 2022 Oct 12;30(10):1343-1344. doi: 10.1016/j.chom.2022.09.005.
Caenorhabditis elegans do not grow on either Staphylococcus saprophyticus or heat-killed Escherichia coli, but do so when exposed to both. In this issue of Cell Host & Microbe, Geng and colleagues have identified E. coli-derived signals as well as the host's neural and innate immunity pathways that promote digestion of S. saprophyticus.
秀丽隐杆线虫既不能在腐生葡萄球菌或热灭活大肠杆菌上生长,但在同时接触这两种细菌时可以生长。在本期《细胞宿主与微生物》中,耿和同事们确定了大肠杆菌衍生的信号以及宿主的神经和先天免疫途径,这些信号和途径促进了腐生葡萄球菌的消化。