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[不可治愈性乳腺肿瘤的雄激素治疗。对照临床研究:南诺龙 - 睾酮内酯 - 去氢表雄酮]

[Androgen therapy of incurable breast neoplasms. Controlled clinical study: nandrolone-testololactone-drostanolone].

作者信息

Wolff G, Rieche K

出版信息

Onkologie. 1978 Aug;1(4):172-4. doi: 10.1159/000213943.

Abstract

In 91 patients with advanced breast cancer testololactone, drostanolone, and nandrolone were compared in a controlled clinical trial. Remissions were registered after 4 weeks and after another 12 week period; during this second interval the patients received an additional treatment with cyclophosphamide. There was no difference in the effectivity between the three drugs. Remission rate was in average after 4 weeks 24% and after 16 weeks 46%.

摘要

在一项对照临床试验中,对91例晚期乳腺癌患者使用睾酮内酯、羟甲雄酮和诺龙进行了比较。在4周后以及随后的12周期间记录缓解情况;在这第二个时间段,患者接受了环磷酰胺的额外治疗。三种药物之间的有效性没有差异。缓解率在4周后平均为24%,在16周后为46%。

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