Mikhaĭlov A T
Ontogenez. 1978;9(5):439-48.
Antisera were obtained to the total extract and individual electrophoretic fractions of lens proteins: alpha-, beta-, gamma1- and gamma2-crystallins. The crystallins under study are immunochemically heterogenous: each class of lens proteins contains 2--4 antigens. Using the indirect method of fluorescent antibodies, it was established that the appearance of crystallins during development coincided with the onset of formation of the presumptive lens fibers. No crystallins were found in the lens placode and early lens vesicle. gamma-Crystallins appear later than the other lens proteins and are characteristic, mainly, for the lens fibers; at the advanced stages of organogenesis gamma-crystallins are regularly found in the epithelial cells of the developing lens as well.
α-、β-、γ1-和γ2-晶状体蛋白。所研究的晶状体蛋白在免疫化学上是异质的：每一类晶状体蛋白都包含2至4种抗原。采用荧光抗体间接法确定，晶状体蛋白在发育过程中的出现与假定晶状体纤维形成的开始时间一致。在晶状体原基和早期晶状体泡中未发现晶状体蛋白。γ-晶状体蛋白比其他晶状体蛋白出现得晚，主要是晶状体纤维的特征性蛋白；在器官发生的后期阶段，γ-晶状体蛋白也经常出现在发育中晶状体的上皮细胞中。
