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[压力与基因变异性]

[Stress and genetic variability].

作者信息

Borodin P M

出版信息

Genetika. 1987 Jun;23(6):1003-10.

PMID:3623091
Abstract

It was shown by D.K. Belyaev and the coworkers that stress can lead to changes in the degree of manifestation of genetic variation in a number of quantitative traits, such as fertility, growth rate and endocrine functions. The effects of emotional stress on the meiotic process in male mice were established. Stress inhibits both replication and repair of DNA at corresponding stages of meiosis. These are the reasons for an increase in X-Y and autosomal univalent frequency and recombination frequency in the 1-st and 2-nd chromosomes. Thus, stress leads to redistribution of recombination frequencies in the genome and produces the new spectrum of combination variation. The data presented support the concept of D.K. Belyaev that stress has substantial influence on the rate of evolution.

摘要

D.K. 别利亚耶夫及其同事的研究表明,压力会导致许多数量性状的遗传变异表现程度发生变化,如生育力、生长速率和内分泌功能。研究确定了情绪压力对雄性小鼠减数分裂过程的影响。压力会抑制减数分裂相应阶段的DNA复制和修复。这些就是X - Y染色体和常染色体单价频率以及第一和第二染色体重组频率增加的原因。因此,压力会导致基因组中重组频率的重新分布,并产生新的组合变异谱。所呈现的数据支持了D.K. 别利亚耶夫的观点,即压力对进化速率有重大影响。

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