Torabinejad M, Bakland L K
Oral Surg Oral Med Oral Pathol. 1978 Nov;46(5):685-99. doi: 10.1016/0030-4220(78)90465-6.
The pathogenesis of periapical lesions has not been fully elucidated. Currently, the possibility of its being an immunologic phenomenon is receiving much attention. This article presents a review of the literature concerning immunologic reactions which may involve periapical lesions. It appears that antigen-antibody complexes and IgE-mediated reactions can initiate preliminary changes in periapical tissues. It is also likely that delayed hypersensitivity participates in the perpetuation and progression of periapical disease.
根尖周病变的发病机制尚未完全阐明。目前,其作为一种免疫现象的可能性正受到广泛关注。本文对可能涉及根尖周病变的免疫反应的文献进行综述。抗原 - 抗体复合物和IgE介导的反应似乎可引发根尖周组织的初步变化。迟发型超敏反应也很可能参与根尖周病的持续和进展。