牙髓根尖周病的免疫学方面。综述。

Immunologic aspects of pulpal-periapical diseases. A review.

作者信息

Morse D R

出版信息

Oral Surg Oral Med Oral Pathol. 1977 Mar;43(3):436-51. doi: 10.1016/0030-4220(77)90331-0.

PMID:320531

Abstract

The relationship of immunologic concepts to endodontic diseases is discussed. Immunologic mechanisms are considered, including antigens, haptens, antibodies, and cell-mediated responses. Studies of immunologic manifestations in endodontic diseases are given. These include (1) localization of plasma proteins in inflammed human dental pulp, (2) introduction of microbes into animal root canals, (3) introduction of non-microbial antigens into animal root canals, (4) introduction of root canal antigens into human beings, (5) introduction of root canal antigens into animals, (6) studies of "focal" infection, (7) examination of serum antibodies, (8) examination of periapical lesions, and (9) a cell-mediated study. Next, immunologic concepts related to periapical pathosis are considered. Finally, preventive and treatment concepts are reviewed.

摘要

讨论了免疫学概念与牙髓病的关系。对免疫机制进行了探讨，包括抗原、半抗原、抗体和细胞介导的反应。给出了牙髓病免疫表现的研究。这些研究包括：（1）血浆蛋白在人类炎症牙髓中的定位；（2）将微生物引入动物根管；（3）将非微生物抗原引入动物根管；（4）将根管抗原引入人体；（5）将根管抗原引入动物；（6）“局灶性”感染的研究；（7）血清抗体检测；（8）根尖周病变检查；（9）细胞介导的研究。接下来，考虑了与根尖周病变相关的免疫学概念。最后，回顾了预防和治疗概念。