Landsverk T
Immunol Cell Biol. 1987 Jun;65 ( Pt 3):251-61. doi: 10.1038/icb.1987.28.
Significant differences were found between the follicle-associated epithelial cells (FAE) covering the domes of the jejunal and ileal Peyer's patches (PP) in calves. Whereas the FAE of the jejunal PP had scattered membraneous (M) cells among absorptive epithelial cells, the FAE of the ileal PP constituted a homogeneous population of cells different from both absorptive cells and M cells. The FAE of the ileal PP had short microvilli or folds, cytoplasmic vesicles and vacuoles containing acid phosphatase. Fifty nanometer membrane-bounded particles were found in lacunae extending from the lateral cell border. These particles appeared to have been shed from the FAE. Finger-like projections, rich in microfilaments, extended into the lacunae. M cells had short, sparse microvilli, many vesicles, few lysosomal structures, and they enfolded groups of mononuclear leucocytes. Transcytosis of macromolecular tracers occurred in both M cells and in the FAE of the ileal PP, though the uptake was greater in the latter. The 50 nm particles were also found between cells in the lymphoid tissue underneath the FAE of the ileal PP. The FAE of PP in pre- and post-natal lambs from 115 days of gestation and onwards, and goat kids, showed similar structural features.
在犊牛空肠和回肠派伊尔结（PP）穹顶覆盖的滤泡相关上皮细胞（FAE）之间发现了显著差异。空肠PP的FAE在吸收性上皮细胞中有散在的膜性（M）细胞，而回肠PP的FAE则构成了一个与吸收性细胞和M细胞均不同的同质细胞群体。回肠PP的FAE有短微绒毛或褶皱、含有酸性磷酸酶的胞质小泡和液泡。在从细胞外侧边界延伸的腔隙中发现了50纳米的膜结合颗粒。这些颗粒似乎是从FAE脱落的。富含微丝的指状突起延伸到腔隙中。M细胞有短而稀疏的微绒毛、许多小泡、很少的溶酶体结构，并且它们包绕着单核白细胞群。大分子示踪剂的转胞吞作用在M细胞和回肠PP的FAE中均有发生，尽管后者的摄取量更大。在回肠PP的FAE下方淋巴组织的细胞之间也发现了50纳米的颗粒。妊娠115天及以后的产前和产后羔羊以及山羊幼崽的PP的FAE表现出相似的结构特征。
