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《哥伦比亚乳胶脱蛋白处理的改进：文献计量学研究》

Improving Deproteinization in Colombian Latex from : A Bibliometric Approximation.

作者信息

Hernandez-Tenorio Fabian, Arroyave-Miranda Héctor, Miranda Alejandra M, González Sandra M, Rodríguez Carlos A, Sáez Alex A

机构信息

School of Applied Sciences and Engineering, Universidad EAFIT, Medellín 050022, Colombia.

Biological Sciences and Bioprocesses Group, School of Applied Sciences and Engineering, Universidad de EAFIT, Medellín 050022, Colombia.

出版信息

Polymers (Basel). 2022 Oct 10;14(19):4248. doi: 10.3390/polym14194248.

DOI:10.3390/polym14194248
PMID:36236196
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9573318/
Abstract

Natural Rubber Field Latex (NRFL) allergens restrict its use in some markets due to health-threatening allergic reactions. These molecules are proteins that are related to asymptomatic sensitization and hypersensitivity mediated by immunoglobulin E (IgE). Although NRFL allergens have been investigated since the 1980s, there are still gaps in knowledge regarding the development of deproteinized natural rubber (DPNR). Therefore, in this study, the deproteinization of NRFL from the lower basin of the Cauca River, Antioquia-Colombia was evaluated using eight systems. The highest removal value was 84.4% and was obtained from the treatment containing SDS (Sodium dodecyl sulfate), Urea, and Ethanol. It was also possible to determine that at high concentrations of SDS, removal percentages higher than 70% are reached. On the other hand, all deproteinizing systems decreased NRFL Zeta potentials without self-coagulation, suggesting enhanced colloidal stability in DPNR latex. On the other hand, the bibliometric analysis presented technological advances in DPRN through different parameters and bibliometric networks. The analysis presented makes an important contribution from the bibliometric approach that could be positive for the development of research on DPNR.

摘要

天然橡胶田间乳胶（NRFL）过敏原因其会引发威胁健康的过敏反应而限制了其在某些市场的使用。这些分子是与由免疫球蛋白E（IgE）介导的无症状致敏和超敏反应相关的蛋白质。尽管自20世纪80年代以来就对NRFL过敏原进行了研究，但关于脱蛋白天然橡胶（DPNR）的发展在知识方面仍存在空白。因此，在本研究中，使用八种体系对来自哥伦比亚安蒂奥基亚省考卡河下游流域的NRFL进行了脱蛋白评估。最高去除率为84.4%，是从含有十二烷基硫酸钠（SDS）、尿素和乙醇的处理中获得的。还能够确定，在高浓度SDS的情况下，去除率可达到70%以上。另一方面，所有脱蛋白体系均降低了NRFL的zeta电位且未出现自凝聚现象，这表明DPNR乳胶的胶体稳定性增强。另一方面，文献计量分析通过不同参数和文献计量网络展示了DPNR的技术进展。所呈现的分析从文献计量方法上做出了重要贡献，这可能对DPNR的研究发展具有积极意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20fb/9573318/10e147bb9a26/polymers-14-04248-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20fb/9573318/05cea8dd8171/polymers-14-04248-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20fb/9573318/a7276e8acf80/polymers-14-04248-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20fb/9573318/d1dc67587f92/polymers-14-04248-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20fb/9573318/96b797768b6a/polymers-14-04248-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20fb/9573318/6af676d8bdbc/polymers-14-04248-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20fb/9573318/2a30b5e57435/polymers-14-04248-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20fb/9573318/758fd6f8b288/polymers-14-04248-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20fb/9573318/254d36b89949/polymers-14-04248-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20fb/9573318/44a72fe61c3c/polymers-14-04248-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20fb/9573318/10e147bb9a26/polymers-14-04248-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20fb/9573318/05cea8dd8171/polymers-14-04248-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20fb/9573318/a7276e8acf80/polymers-14-04248-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20fb/9573318/d1dc67587f92/polymers-14-04248-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20fb/9573318/96b797768b6a/polymers-14-04248-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20fb/9573318/6af676d8bdbc/polymers-14-04248-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20fb/9573318/2a30b5e57435/polymers-14-04248-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20fb/9573318/758fd6f8b288/polymers-14-04248-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20fb/9573318/254d36b89949/polymers-14-04248-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20fb/9573318/44a72fe61c3c/polymers-14-04248-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20fb/9573318/10e147bb9a26/polymers-14-04248-g010.jpg

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