Bauer C R, Fojaco R M, Bancalari E, Fernandez-Rocha L
Pediatrics. 1978 Oct;62(4):574-7.
The case of an infant born in association with a large chorioangioma of the placenta is presented. The maternal complications of polyhydramnios, preeclampsia, and premature labor are those described in the "syndrome" of a chorioangioma. The immediate neonatal course was unusually complicated by severe microangiopathic anemia with persistent thrombocytopenia and hemolysis which required three exchange blood transfusions. The relationship between the neonatal complications and the placental tumor is discussed in terms of possible pathophysiologic mechanisms.
本文报告了一例与胎盘巨大绒毛膜血管瘤相关的婴儿出生病例。羊水过多、先兆子痫和早产等母亲并发症是绒毛膜血管瘤“综合征”中所描述的情况。新生儿期即刻病程异常复杂，出现严重微血管病性贫血，伴有持续性血小板减少和溶血，需要进行三次换血输血。从可能的病理生理机制方面讨论了新生儿并发症与胎盘肿瘤之间的关系。
