Schultz R J, Johnston A D, Krishnamurthy S
Int Orthop. 1987;11(3):277-82. doi: 10.1007/BF00271461.
This study was designed to investigate the thermal effects of polymerization on small tubular bones. The results demonstrated only a slight increase in temperature during cement-curing in the medullary canals of these bones. The maximum rise (11.7 degrees C) was within the levels of tolerance for living bone cells. It was demonstrated that the small volumes of methyl-methacrylate cool more rapidly, hence further decreasing the deleterious effects of heat. The histological studies showed no recognisable adverse reaction to the thermal effects of methyl-methacrylate polymerization on small tubular bones or on the overlying tissue.
本研究旨在调查聚合反应对小管状骨的热效应。结果表明，在这些骨骼的髓腔内进行骨水泥固化过程中，温度仅略有升高。最大升温幅度（11.7摄氏度）处于活骨细胞的耐受范围内。结果表明，少量的甲基丙烯酸甲酯冷却速度更快，从而进一步降低了热的有害影响。组织学研究表明，甲基丙烯酸甲酯聚合反应产生的热效应，对小管状骨或其上方组织未产生明显的不良反应。
