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[帕金森病的磁共振成像表现：黑质纹状体变性的影像学评估]

[MRI Findings in Parkinson's Disease: Radiologic Assessment of Nigrostriatal Degeneration].

作者信息

Bae Yun Jung, Kim Jong-Min, Choi Byung Se, Song Yoo Sung, Nam Yoonho, Cho Se Jin, Kim Jae Hyoung, Kim Sang Eun

出版信息

Taehan Yongsang Uihakhoe Chi. 2022 May;83(3):508-526. doi: 10.3348/jksr.2022.0044. Epub 2022 May 25.

DOI:10.3348/jksr.2022.0044
PMID:36238511
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9514534/
Abstract

Parkinson's disease (PD) is a movement disorder that develops due to degenerative loss of dopaminergic cells in the substantia nigra of the midbrain. Recent advances in MRI techniques have demonstrated various imaging findings that can reflect the underlying pathophysiological processes occurring in Parkinson's disease. Many imaging studies have shown that such findings can assist in the diagnosis of Parkinson's disease and its differentiation from atypical parkinsonism. In this review, we present MRI techniques that can be used in clinical assessment, such as nigrosome imaging and neuromelanin imaging, and we provide the detailed imaging features of Parkinson's disease reflecting nigrostriatal degeneration.

摘要

帕金森病（PD）是一种运动障碍性疾病，由于中脑黑质多巴胺能细胞的退行性丧失而发病。MRI技术的最新进展已显示出各种影像学表现，这些表现能够反映帕金森病中发生的潜在病理生理过程。许多影像学研究表明，这些表现有助于帕金森病的诊断及其与非典型帕金森综合征的鉴别。在本综述中，我们介绍了可用于临床评估的MRI技术，如黑质成像和神经黑色素成像，并提供了反映黑质纹状体变性的帕金森病详细影像学特征。

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Alterations in white matter fiber in Parkinson disease across different cognitive stages.帕金森病不同认知阶段的白质纤维改变。
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Iron-sensitive magnetic resonance imaging in Parkinson's disease: a systematic review and meta-analysis.
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Brain. 2021 Jun 22;144(5):1488-1497. doi: 10.1093/brain/awab039.
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