Zhu Zhonglun, Wang Zhicong, Wu Yuxuan, Chen Xi, Liu Hailong, Zhang Jianjun, Liu Mozhen, Liu Yuehong
Department of Orthopedics, People's Hospital of Deyang City, Deyang, People's Republic of China.
Department of Orthopedics, The First Affiliated Hospital of Dalian Medical University, Dalian, People's Republic of China.
Int J Gen Med. 2022 Oct 7;15:7693-7700. doi: 10.2147/IJGM.S384862. eCollection 2022.
Widowed people have increased mortality than married people of the same age, a phenomenon known as the widowhood effect. This study aimed to investigate whether this effect exists in older patients with hip fracture.
Using our own hip fracture database, a total of 1101 hip fracture patients were consecutively included from January 2014 to December 2021. Marital status was stratified as married (n = 793) and widowed (n = 308). Patients survival status was obtained from medical records or telephone follow-ups, and the outcomes were all-cause mortality at 30 days, 1 year and at latest follow-up. Univariate and multivariate Cox proportional hazard models were used to assess the association between marital status and mortality, and subgroup analyses according to sex were also conducted.
Compared with married patients, widowed patients were more likely to be older, female and intertrochanteric fracture, and were less likely to be urban area, smoking, drinking, and surgical treatment ( < 0.05). After a median follow-up of 37.1 months, the 30-day mortality was 4.3% (n = 47), 1-year mortality was 19.3% (n = 178), and total mortality was 34.2% (n = 376). Multivariate Cox analysis showed that widowed marital status remained an independent risk factor for 1-year mortality ( = 1.437, 95% : 1.054-1.959, = 0.022), and total mortality ( = 1.296, 95% : 1.038-1.618, = 0.022), whereas this association was not found in 30-day mortality ( = 1.200, 95% : 0.607-2.376, = 0.599). Moreover, subgroup analyses also found that the widowhood effect on mortality was present in both male and female.
Widowed marital status seems to be an independent risk factor for long-term mortality in older patients with hip fracture.
丧偶者的死亡率高于同龄已婚者,这一现象被称为丧偶效应。本研究旨在调查这种效应在老年髋部骨折患者中是否存在。
利用我们自己的髋部骨折数据库,从2014年1月至2021年12月连续纳入了1101例髋部骨折患者。婚姻状况分为已婚(n = 793)和丧偶(n = 308)。通过病历或电话随访获取患者的生存状况,结局指标为30天、1年及末次随访时的全因死亡率。采用单因素和多因素Cox比例风险模型评估婚姻状况与死亡率之间的关联,并按性别进行亚组分析。
与已婚患者相比,丧偶患者年龄更大、女性更多、转子间骨折更多,且居住在城市、吸烟、饮酒及接受手术治疗的可能性更小(P < 0.05)。中位随访37.1个月后,30天死亡率为4.3%(n = 47),1年死亡率为19.3%(n = 178),总死亡率为34.2%(n = 376)。多因素Cox分析显示,丧偶婚姻状况仍是1年死亡率(HR = 1.437,95%CI:1.054 - 1.959,P = 0.022)和总死亡率(HR = 1.296,95%CI:1.038 - 1.618,P = 0.022)的独立危险因素,而在30天死亡率中未发现这种关联(HR = 1.200,95%CI:0.607 - 2.376,P = 0.599)。此外,亚组分析还发现丧偶效应在男性和女性中均存在。
丧偶婚姻状况似乎是老年髋部骨折患者长期死亡率的独立危险因素。