Lee Ji Eun, Kim Seong Hyun, Lee Soon Jin, Choi Seo-Youn, Lee Sunyoung, Lee Bo Ra
Taehan Yongsang Uihakhoe Chi. 2021 May;82(3):638-653. doi: 10.3348/jksr.2020.0078. Epub 2021 Feb 28.
To compare the recurrence pattern, disease-free survival (DFS), and overall survival (OS) after curative surgery for pancreatic ductal adenocarcinoma (PDAC) in patients who underwent preoperative evaluation with CT alone or in combination with MRI, and to compare the prognosis according to the first recurrence site.
We retrospectively evaluated 152 patients who underwent R0 resection of PDAC. Preoperative CT or combined CT and MRI were performed for 103 and 49 patients, respectively. Two radiologists recorded the location and date of the first recurrence in consensus. The recurrence pattern, DFS, and OS were compared between the two groups. OS was analyzed according to the first recurrence site.
In both groups, liver metastasis was the most common recurrence pattern. DFS ( = 0.247) or OS ( = 0.067) showed no significant difference between the two groups. OS according to the first recurrence site was the lowest for liver metastasis, followed by locoregional recurrence ( < 0.001).
There were no significant differences in the recurrence pattern, DFS, or OS between patients evaluated with preoperative CT alone or with CT and MRI after curative resection of PDAC. Liver metastasis was the most common tumor recurrence pattern with the lowest OS.
比较仅接受术前CT评估或接受CT与MRI联合评估的胰腺导管腺癌（PDAC）患者在根治性手术后的复发模式、无病生存期（DFS）和总生存期（OS），并根据首次复发部位比较预后。
我们回顾性评估了152例行PDAC根治性R0切除的患者。分别对103例和49例患者进行了术前CT或CT与MRI联合检查。两名放射科医生就首次复发的部位和日期达成一致记录。比较两组的复发模式、DFS和OS。根据首次复发部位分析OS。
两组中，肝转移都是最常见的复发模式。两组间DFS（ = 0.247）或OS（ = 0.067）无显著差异。根据首次复发部位，肝转移患者的OS最低，其次是局部区域复发（ < 0.001）。
PDAC根治性切除术后，仅接受术前CT评估或接受CT与MRI联合评估的患者在复发模式、DFS或OS方面无显著差异。肝转移是最常见的肿瘤复发模式，且OS最低。
