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免疫球蛋白G4相关性疾病累及头颈部多个区域：一例报告

Immunoglobulin G4-Related Disease Involving Various Head and Neck Regions: A Case Report.

作者信息

Im Jun Yong, Sunwoo Miok

出版信息

J Korean Soc Radiol. 2022 Jul;83(4):910-917. doi: 10.3348/jksr.2021.0107. Epub 2022 Feb 25.

DOI:10.3348/jksr.2021.0107
PMID:36238908
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9514576/
Abstract

Immunoglobulin G4 (IgG4) related disease (IgG4-RD) is currently considered an immune-mediated condition and is recognized as a disorder group with common pathological, hematological, and clinical characteristics. This disease may involve diverse organs of the head and neck, and include mainly the lacrimal gland, orbit, thyroid gland, pituitary gland, and the meninges. Here, we report a case of IgG4-RD in a 65-year-old female showing head- and neck-limited but synchronously and mainly manifesting as otalgia and facial neuritis.

摘要

免疫球蛋白G4（IgG4）相关疾病（IgG4-RD）目前被认为是一种免疫介导的病症，并且被公认为是具有共同病理、血液学和临床特征的一组疾病。该疾病可能累及头颈部的多种器官，主要包括泪腺、眼眶、甲状腺、垂体和脑膜。在此，我们报告一例65岁女性的IgG4-RD病例，该病例局限于头颈部，但同时主要表现为耳痛和面部神经炎。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3df8/9514576/433beeee2b06/jksr-83-910-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3df8/9514576/433beeee2b06/jksr-83-910-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3df8/9514576/433beeee2b06/jksr-83-910-g001.jpg

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Int J Environ Res Public Health. 2020 Nov 5;17(21):8179. doi: 10.3390/ijerph17218179.
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IgG4-related lymphadenopathy: a potentially under- and over-diagnosed entity.IgG4相关性淋巴结病：一种可能诊断不足和过度诊断的疾病实体。
Int J Clin Exp Pathol. 2017 Oct 1;10(10):10153-10166. eCollection 2017.
3
Immunoglobulin G4-related hypertrophic pachymeningitis: A case-oriented review.
免疫球蛋白 G4 相关肥厚性硬脑膜炎：基于病例的综述。
Neurol Neuroimmunol Neuroinflamm. 2019 May 7;6(4):e568. doi: 10.1212/NXI.0000000000000568. eCollection 2019 Jul.
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Idiopathic hypertrophic pachymeningitis: an autoimmune IgG4-related disease.特发性肥厚性硬脑膜炎：一种自身免疫性IgG4相关疾病。
Immunol Res. 2017 Feb;65(1):386-394. doi: 10.1007/s12026-016-8863-1.
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IgG4-related disease.IgG4 相关疾病。
Lancet. 2015 Apr 11;385(9976):1460-71. doi: 10.1016/S0140-6736(14)60720-0. Epub 2014 Dec 4.
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