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12只犬经睑下冲洗置管进行眼部药物远程局部给药:一项回顾性研究及对主人认知的评估

Subpalpebral lavage placement for remote topical administration of ocular medications in 12 dogs: A retrospective review and assessment of owner perception.

作者信息

Parker Josie, Ioannides Joy, Kumaratunga Vim, Preston Juliette, Hartley Claudia, Donaldson David

机构信息

Ophthalmology Department, Hospital for Small Animals Royal (Dick) School of Veterinary Studies, University of Edinburgh, Roslin, UK.

Optivet Referrals, Havant, UK.

出版信息

Vet Ophthalmol. 2023 Mar;26(2):108-120. doi: 10.1111/vop.13029. Epub 2022 Oct 14.

Abstract

OBJECTIVE

The aim of this study was to describe the placement of subpalpebral lavage (SPL) systems in 12 dogs (15 eyes) intolerant of topical ocular medications to assess the suitability, complications encountered and owner perception of use.

ANIMALS STUDIED

Retrospective review of dogs that underwent SPL placement for treatment of ocular disease at the Ophthalmology Department, University of Bristol Small Animal Hospital between 2017 and 2021.

PROCEDURE(S): Data recorded included signalment, history, diagnosis, treatment, reason for SPL placement, uni- or bilateral placement, duration of placement, complications, and outcome. Owner perception was assessed using an online questionnaire. Statistical analysis included McNemar and Wilcoxon signed-ranks tests.

RESULTS

Twelve dogs (15 eyes) underwent SPL placement. Eleven owners completed the online questionnaire. Corneal ulceration was the most common disease requiring SPL placement (n = 13/15 eyes, 86.7%). Most cases received multimodal topical therapy (n = 9/15 eyes, 60.0%) via SPL. Owners administered medication 6.63 times daily via SPL (range 1-16 applications/day). All dogs requiring ongoing topical medication (n = 8/12, 66.7%) were trained to accept direct administration during SPL treatment. Statistically significant improvements in medication compliance, ease of application, and reduced perceived risk of iatrogenic ocular injury were reported by owners (p-value = .001, .004, and .031 respectively). Minor complications were infrequently reported but an excellent outcome was achieved for all eyes.

CONCLUSION

Subpalpebral lavage placement provides a practical and safe solution for the provision of frequent multimodal ocular medication when treating patients with a challenging temperament.

摘要

目的

本研究旨在描述12只对局部眼用药物不耐受的犬(15只眼)的睑下冲洗(SPL)系统放置情况,以评估其适用性、所遇到的并发症以及主人对使用的看法。

研究动物

对2017年至2021年期间在布里斯托大学小动物医院眼科接受SPL放置以治疗眼部疾病的犬进行回顾性研究。

方法

记录的数据包括特征、病史、诊断、治疗、放置SPL的原因、单侧或双侧放置、放置持续时间、并发症及结果。使用在线问卷评估主人的看法。统计分析包括McNemar检验和Wilcoxon符号秩检验。

结果

12只犬(15只眼)接受了SPL放置。11位主人完成了在线问卷。角膜溃疡是最常见的需要放置SPL的疾病(13/15只眼,86.7%)。大多数病例通过SPL接受多模式局部治疗(9/15只眼,60.0%)。主人通过SPL每天给药6.63次(范围为1 - 16次/天)。所有需要持续局部用药的犬(8/12,66.7%)在SPL治疗期间接受了直接给药的训练。主人报告在用药依从性、给药 ease、以及降低医源性眼损伤的感知风险方面有统计学显著改善(p值分别为0.001、0.004和0.031)。很少报告轻微并发症,但所有眼睛均取得了良好的结果。

结论

睑下冲洗放置为治疗性情具有挑战性的患者时提供频繁多模式眼用药物提供了一种实用且安全的解决方案。

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