Hempelmann G, Frerk C, Piepenbrock S, Schleussner E
Prakt Anaesth. 1978 Oct;13(5):437-45.
In 24 patients with congenital or acquired heart disease, functional class II--IV New York Heart Association Classification, effects of aminophylline on hemodynamics have been investigated intraoperatively, during extracorporeal circulation and postoperatively. Aminophylline caused a decrease in arterial pressure, left ventricular pressure, right and left atrial pressure, total systemic resistance and total pulmonary resistance. At the same time there was an increase in heart peak, peak dp/dt, cardiac index and stroke index. Our results demonstrate beneficial cardiac and extracardiac effects of aminophylline in man.
对24例先天性或后天性心脏病患者(纽约心脏协会心功能分级为II - IV级),在体外循环期间及术后术中研究了氨茶碱对血流动力学的影响。氨茶碱可使动脉压、左心室压、左右心房压、总体循环阻力和总肺循环阻力降低。同时,心搏峰、dp/dt峰、心脏指数和每搏指数增加。我们的结果表明氨茶碱对人体心脏和心脏外有有益作用。