快照：癌症免疫编辑。

SnapShot: Cancer immunoediting.

机构信息

The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.

University of California, San Diego, La Jolla, CA 92093, USA.

出版信息

Cell. 2022 Oct 13;185(21):4038-4038.e1. doi: 10.1016/j.cell.2022.09.027.

DOI:10.1016/j.cell.2022.09.027

PMID:36240741

Abstract

In the tumor microenvironment, immune cells and tumor cells interact in a process called cancer immunoediting, giving rise to changes in gene expression, metabolism, mutational burden, and cellularity in the tumor. This SnapShot compares endogenous versus therapy-induced cancer immunoediting and outlines the molecular and cellular characteristics of interactions that result in complete tumor regression versus tumor escape and progression. To view this SnapShot, open or download the PDF.

摘要

在肿瘤微环境中，免疫细胞和肿瘤细胞在一个称为癌症免疫编辑的过程中相互作用，导致肿瘤中基因表达、代谢、突变负担和细胞组成的变化。这篇SnapShot 比较了内源性与治疗诱导的癌症免疫编辑，并概述了导致完全肿瘤消退与肿瘤逃逸和进展的相互作用的分子和细胞特征。要查看此 SnapShot，请打开或下载 PDF。