Cohen Children's Medical Center (HH Bernstein, EJ Slora, T Mathias-Prabhu, and HS Park), New Hyde Park, NY; Zucker School of Medicine at Hofstra/Northwell (HH Bernstein), Hempstead, NY.
Cohen Children's Medical Center (HH Bernstein, EJ Slora, T Mathias-Prabhu, and HS Park), New Hyde Park, NY.
Acad Pediatr. 2023 Mar;23(2):343-350. doi: 10.1016/j.acap.2022.10.005. Epub 2022 Oct 12.
The association of maternal severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) status before delivery with breastfeeding is unknown. This study compares breastfeeding initiation, exclusivity, and duration between SARS-CoV-2-positive (+) and SARS-CoV-2-negative (-) mothers during the first 2 months of their newborns' lives.
A single center, retrospective cohort study of pediatric contacts during the first 2 months in a diverse mother-infant population (n = 285) compared breastfeeding outcomes by maternal SARS-CoV-2 status during a pandemic surge. Infants of SARS-CoV-2 positive mothers were also tested before discharge. Comparison of maternal demographics (age, race, ethnicity), maternal/infant characteristics (parity, insurance, delivery mode, infant sex, hospital length of stay), and pediatric contacts by maternal SARS-CoV-2 status included Fisher's exact and Wilcoxon tests and Poisson regression for count outcomes. Logistic regression compared breastfeeding outcomes between the 2 groups, adjusting for potential confounders and effect modifiers.
Maternal demographics and maternal/infant characteristics were similar. While 19% of mothers tested positive for SARS-CoV-2 (n = 54), their infants were all negative. SARS-CoV-2 positive mothers had fewer in-person, but more virtual pediatric contacts. After controlling for the above variables, SARS-CoV-2 positive mothers had lower odds of breastfeeding initiation within 1 to 7 days of life (78% vs 88%; adjusted odds ratio [aOR] = 0.40, 95% confidence interval [CI]: 0.17, 0.96) and of any breastfeeding during month 2 (54% vs 76%; aOR = 0.37, 95% CI: 0.16, 0.86) compared with SARS-CoV-2 negative mothers.
Maternal SARS-CoV-2 positivity at delivery was independently associated with less initiation and shorter duration of any breastfeeding during month 2. SARS-CoV-2 positive women would likely benefit from additional breastfeeding support during pandemic surges.
产妇分娩前严重急性呼吸综合征冠状病毒 2（SARS-CoV-2）状态与母乳喂养的关系尚不清楚。本研究比较了在新生儿生命的头 2 个月内 SARS-CoV-2 阳性（+）和 SARS-CoV-2 阴性（-）母亲的母乳喂养起始、排他性和持续时间。
在一个多样化的母婴人群中，对前 2 个月的儿科接触者进行了一项单中心回顾性队列研究（n=285），比较了在大流行期间 SARS-CoV-2 阳性母亲的母乳喂养结果。SARS-CoV-2 阳性母亲的婴儿在出院前也接受了检测。比较 SARS-CoV-2 状态下的产妇人口统计学特征（年龄、种族、民族）、产妇/婴儿特征（产次、保险、分娩方式、婴儿性别、住院时间）和儿科接触者，包括 Fisher 精确检验和 Wilcoxon 检验以及泊松回归计数结果。逻辑回归比较了两组之间的母乳喂养结果，调整了潜在的混杂因素和效应修饰因素。
产妇人口统计学特征和产妇/婴儿特征相似。虽然有 19%的母亲检测出 SARS-CoV-2 阳性（n=54），但她们的婴儿均为阴性。SARS-CoV-2 阳性母亲的面对面儿科接触较少，但虚拟儿科接触较多。在控制上述变量后，SARS-CoV-2 阳性母亲在生命的头 1-7 天内开始母乳喂养的可能性较低（78%比 88%；调整后的优势比[aOR]为 0.40，95%置信区间[CI]：0.17，0.96），在第 2 个月期间任何母乳喂养的可能性也较低（54%比 76%；aOR 为 0.37，95%CI：0.16，0.86）与 SARS-CoV-2 阴性母亲相比。
产妇分娩前 SARS-CoV-2 阳性与第 2 个月任何母乳喂养的起始和持续时间较短独立相关。SARS-CoV-2 阳性女性在大流行期间可能需要额外的母乳喂养支持。
