Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, California, USA.
Montreal Heart Institute, Université de Montréal, Montreal, Quebec, Canada.
J Card Fail. 2023 Feb;29(2):193-209. doi: 10.1016/j.cardfail.2022.09.014. Epub 2022 Oct 13.
Cardiogenic shock is the most extreme cardiovascular disease state during pregnancy. Peripartum cardiomyopathy is the most common cause of cardiogenic shock toward the end of pregnancy and in the early postpartum period. Therapy for cardiogenic shock relies on appropriate phenotyping of shock etiology, severity and ventricular predominance, which are critical in the appropriate selection of medical and mechanical therapy. Mechanical circulatory support may be used as a bridge to recovery or as definitive therapy. Intra-aortic balloon pumps, percutaneous left ventricular assist devices and venoarterial extracorporeal circulatory devices have been successfully used in pregnancy and the postpartum period. The most commonly used mechanical therapy in the pregnant patient is extracorporeal membranous oxygenation circulatory support. The use of mechanical circulatory devices in peripartum cardiomyopathy has contributed to improved survival rates in recent years. Further efforts to identify the optimal mechanical circulatory support strategy for peripartum cardiomyopathy and cardiogenic shock in the peripartum period are needed.
心原性休克是妊娠期间最极端的心血管疾病状态。围产期心肌病是妊娠末期和产后早期心原性休克最常见的原因。心原性休克的治疗依赖于对休克病因、严重程度和心室优势的适当表型分析,这对于选择适当的药物和机械治疗至关重要。机械循环支持可作为恢复的桥梁或作为确定性治疗。主动脉内球囊泵、经皮左心室辅助装置和静脉动脉体外循环装置已成功应用于妊娠和产后。在孕妇中最常用的机械治疗是体外膜氧合循环支持。近年来,机械循环装置在心源性休克中的应用提高了生存率。需要进一步努力确定围产期心肌病和心原性休克的最佳机械循环支持策略。