Najam Usman S, Kim Jitae A, Kim Sophie Y, Wander Gurleen, Rodriguez Mario, Virk Hafeez Ul Hassan, Johnson Mark R, Tang W H Wilson, Krittanawong Chayakrit
Department of Internal Medicine, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA.
Division of Cardiovascular Medicine, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA.
Heart Fail Rev. 2025 Mar;30(2):337-351. doi: 10.1007/s10741-024-10466-y. Epub 2024 Nov 12.
Pregnancy is a period of substantial changes to the body's normal physiology, and the failure to adapt to these changes can lead to life-threatening pathology, particularly involving the cardiovascular system. In comparison to pre-pregnancy physiology, pregnant women have increased blood volume and physical demands which exert increased stress on the heart. This is important to consider in women with and without previously diagnosed cardiovascular disease, as the physiologic changes during pregnancy and postpartum can lead to sudden decompensation. The management of heart failure is particularly important as it remains the most common cardiovascular complication during pregnancy and is associated with substantial maternal and fetal morbidity and mortality. This is especially true in patients with pre-existing heart failure, who should receive counseling before conception and in certain cases be advised against pregnancy. For these reasons, healthcare professionals must be well-versed in the different strategies of diagnosis, management, treatment, and monitoring. This review will outline the pathophysiology, diagnostics, management, and general approach to heart failure in pregnant patients.
怀孕是身体正常生理发生重大变化的时期,无法适应这些变化会导致危及生命的病理状况,尤其是涉及心血管系统。与孕前生理状况相比,孕妇血容量增加且身体需求增大,这会给心脏带来更大压力。对于既往有或无心血管疾病诊断的女性而言,这一点都很重要,因为孕期和产后的生理变化可能导致突然失代偿。心力衰竭的管理尤为重要,因为它仍是孕期最常见的心血管并发症,且与孕产妇和胎儿的高发病率及死亡率相关。对于已有心力衰竭的患者更是如此,这些患者在受孕前应接受咨询,某些情况下应被建议避免怀孕。出于这些原因,医疗保健专业人员必须精通诊断、管理、治疗和监测的不同策略。本综述将概述妊娠患者心力衰竭的病理生理学、诊断、管理及一般处理方法。