Xue Huiru, Yang Wen, Zhao Yunfei, Wang Li, Wang Guilian, Zhang Meini, Zhang Hui
First Hospital of Shanxi Medical University, Taiyuan, Shanxi province, China.
First Hospital of Shanxi Medical University, Taiyuan, Shanxi province, China.
Mult Scler Relat Disord. 2022 Dec;68:104192. doi: 10.1016/j.msard.2022.104192. Epub 2022 Sep 23.
Pain is a common symptom of neuromyelitis optica spectrum disorder (NMOSD), but there are relatively few studies on NMOSD pain.
We retrospectively reviewed the medical records of 145 patients with NMOSD admitted to our hospital between July 2016 and June 2019.
The clinical characteristics of pain and factors related to NMOSD were analyzed, revealing that the incidence of pain in NMOSD is high and can be used for disease localization.
Different types of pain occur at different stages of the disease, and serum aquaporin-4 antibody (AQP4-ab) positivity is an independent risk factor for NMOSD pain. Hormones and biological immune agents may also be effective in some cases.
疼痛是视神经脊髓炎谱系障碍（NMOSD）的常见症状，但关于NMOSD疼痛的研究相对较少。
我们回顾性分析了2016年7月至2019年6月期间我院收治的145例NMOSD患者的病历。
分析了疼痛的临床特征及与NMOSD相关的因素，发现NMOSD疼痛发生率高且可用于疾病定位。
不同类型的疼痛发生于疾病的不同阶段，血清水通道蛋白4抗体（AQP4-ab）阳性是NMOSD疼痛的独立危险因素。激素和生物免疫制剂在某些情况下可能也有效。
